Formulation Development of “RUNNY NOSE NAPKIN”

Abstract

Purpose: To examine the efficiency of prepared formulation for cough and cold by comparing with marketed formulation which can be a supportive therapy in Hospitals in cost effective way. The Runny nose napkin is the quite traditional way but not formulated yet for the treatment of sneezing and coughing. Normally for the treatment of any runny nose we uses the antihistaminic agent, anti-tussive drugs, expectorants, but each formulation having its own limitations. We used the common route of inhalation for the drug targeting. Methods: Different concentration of all the ingredients used in formulation was studied for its effectiveness and stability study. The common ingredients including camphor, menthol, eucalyptus oil, cinnamon oil and many others are used in the fixed combination. Results: The ratio is fixed on the trial and error basis for achieving the required therapeutic value. Trials were done on few of the healthy volunteers who were having cough and cold were asked to inhale the napkin containing different combinations of ingredients to different patients. The most effective combination was optimized from the duration of treatment and stability of formulations. Conclusion: These cost effective and more hygienic napkins will be the better health care product.