{"title":"The Peak of Cytochrome-c (Cyt-c) Gene Expression in Inflammatory Stage after Amputation of Digit Tip Mice (Mus musculus)","authors":"T. Novianti, F. D. Wahyuni, I. Jamilah, S. Ilyas","doi":"10.5220/0009566300780082","DOIUrl":null,"url":null,"abstract":": The complexity of the tissue regeneration process requires the activity of cells and energy. The energy obtained from cellular respiration processes. The cellular respiration involves the enzyme has a role transfer an electron. Cytochrome-c (Cyt-c) is an enzyme in the mitochondria inner membrane that has a role in cell respiration and stimulates apoptosis cells. We studied the Cyt-c gene expression in inflammatory phase of tissue regeneration of digit tip mice ( Mus musculus ) after amputation to analyze a role in tissue regeneration. The result of the Cyt-c gene expression reached a peak on day 3. It showed that the tissue regeneration process needs high energy and involves cell apoptosis to stimulate regeneration. The result of ANOVA homogeneity test of Cyt-c gene expression differentt significantly for each growth day (p <0.05).","PeriodicalId":179648,"journal":{"name":"Proceedings of the 1st International Conference on Health","volume":"66 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 1st International Conference on Health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5220/0009566300780082","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
: The complexity of the tissue regeneration process requires the activity of cells and energy. The energy obtained from cellular respiration processes. The cellular respiration involves the enzyme has a role transfer an electron. Cytochrome-c (Cyt-c) is an enzyme in the mitochondria inner membrane that has a role in cell respiration and stimulates apoptosis cells. We studied the Cyt-c gene expression in inflammatory phase of tissue regeneration of digit tip mice ( Mus musculus ) after amputation to analyze a role in tissue regeneration. The result of the Cyt-c gene expression reached a peak on day 3. It showed that the tissue regeneration process needs high energy and involves cell apoptosis to stimulate regeneration. The result of ANOVA homogeneity test of Cyt-c gene expression differentt significantly for each growth day (p <0.05).
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