Rapid diagnosis in thyroid tumors by using touch cytology

Seno Suzan, Al-Bdairi Adnan, Nasani Mohannad, Alhalabi Safa
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Abstract

The study aims to assess the role of imprint cytology in the diagnosis of thyroid nodules and compare it with paraffin Section in the diagnosis of thyroid lesions. It included 40 patients who visited Private Hospitals in Aleppo during the period from April to December 2021. The results indicated that there were 19 patients with thyroid cancer, representing 47.5%, of whom 14 were diagnosed with Papillary Carcinoma, with a percentage of 35%, and 5 cases with Follicular Carcinoma, with a percentage of 12.5%, while the remaining cases included 21 patients with Benign Adenomas at a rate of 52.5%, including 11 cases of Hashimoto’s disease at a rate of 27.5% and 10 cases of Benign Follicular Tumors at a rate of 25%. These results were compared with Paraffin Sections and reached sensitivity, specificity, and accuracy in diagnosis for this technology, 94.73%, 95.23% and 95%, respectively, and the positive predictive value was 94.73%, while the negative predictive value was 95.23%. The results also indicated that this technology is fast in determining the Histologic Grading of Tumor Differentiation, but it does not determine the Histological Type. It also indicated that there was a significant association between gender and the incidence of thyroid tumors, while no significant statistical evidence was observed between age and the possibility of thyroid cancers.
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触摸细胞学对甲状腺肿瘤的快速诊断
本研究旨在探讨印迹细胞学在甲状腺结节诊断中的作用,并与石蜡切片在甲状腺病变诊断中的比较。其中包括在2021年4月至12月期间到阿勒颇私立医院就诊的40名患者。结果显示,甲状腺癌19例,占47.5%,其中乳头状癌14例,占35%,滤泡癌5例,占12.5%,其余21例为良性腺瘤,占52.5%,其中桥本病11例,占27.5%,良性滤泡瘤10例,占25%。结果与石蜡切片比较,该技术的诊断敏感性、特异性和准确性分别为94.73%、95.23%和95%,阳性预测值为94.73%,阴性预测值为95.23%。结果还表明,该技术可以快速确定肿瘤分化的组织学分级,但不能确定肿瘤的组织学类型。研究还表明,性别与甲状腺肿瘤的发病率之间存在显著相关性,而年龄与甲状腺癌的可能性之间没有显著的统计证据。
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