Synthetic Methods for the formation of Heterocyclic Compounds from Oxime Ether Derivatives

Himani Kumari, H. Kumar, K. Sharma
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Abstract

Heterocyclic ring compounds are not only ubiquitous in prime diversity of vital natural products and synthetic pharmaceuticals and thus highly important in organic synthesis. They have an extensive range of applications.  They are mainly used as veterinary products and as agrochemicals. They are also utilized as corrosion inhibitors, sanitizers, antioxidants, dye stuff and as copolymers. They are accustomed as an important source in the synthesis of bioactive organic compounds. Some natural products like antibiotics such as tetracyclines, cephalosporin, penicillin, aminoglycosides, alkaloids such as morphine, vinblastine, atropine, reserpine, tryptamine, reserpine etc. have heterocyclic constituent. Hence, synthesis of heterocyclic compounds from new procedures have been always demanding. Due to wide range of applications of heterocyclic compounds, this study is a survey of literature of last one decade, describing the methods for the heterocyclic ring formation from the oxime ether.
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肟醚衍生物形成杂环化合物的合成方法
杂环化合物不仅广泛存在于多种重要的天然产物和合成药物中,在有机合成中也具有重要意义。它们有广泛的应用范围。它们主要用作兽药产品和农用化学品。它们也被用作缓蚀剂、杀菌剂、抗氧化剂、染料和共聚物。它们通常是合成生物活性有机化合物的重要来源。一些天然产物如抗生素如四环素、头孢菌素、青霉素、氨基糖苷类,生物碱如吗啡、长春碱、阿托品、利血平、色胺、利血平等都含有杂环成分。因此,从新的方法合成杂环化合物一直要求很高。由于杂环化合物的广泛应用,本文对近十年来的文献进行了综述,介绍了肟醚合成杂环的方法。
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