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Agricultural Waste Management by Hydrothermal Carbonization 水热炭化法处理农业废弃物
Pub Date : 2023-05-07 DOI: 10.51611/iars.irj.v12i02.2022.215
W. Raja, Ubhat Ali, Akhil Gupta, Pratik Kumar
There has been a huge emphasis on converting waste into energy in developing countries like India since a couple of decades now. Agriculture is a huge industry in India and produces huge amount of agricultural waste which goes around 350 million tons every year.  Out of this huge weight of waste more than 40 million tons is sugarcane bagasse. Only a small percentage of this waste is collected and out of that, less than 20% gets advanced treatments like incineration, pyrolysis etc. and the rest of it ends up in landfills. In this study Hydrothermal Carbonization of bagasse is carried out in order to raise its carbon content and achieve a higher calorific value. The waste after undergoing the HTC is called hydrochar and mostly resembles the properties of lignite coal. A number of tests are performed on the feedstock at 200 ° C and 220 ° C for three reaction periods viz. 2, 4 and 6 hours. The yield of the char is found to decreases with increase in temperature and retention time whereas the Carbon percentage shows a positive trend and goes as high as 69.1 % at 220° C with Calorific value as 24.44 MJ/kg at 6 hours reaction period.
几十年来,印度等发展中国家一直非常重视将废物转化为能源。农业在印度是一个巨大的产业,每年产生大量的农业废物,约为3.5亿吨。在这些重量巨大的废物中,有4000多万吨是甘蔗渣。只有一小部分垃圾被收集起来,其中不到20%得到焚烧、热解等高级处理,其余的最终被填埋。为了提高甘蔗渣的含碳量,获得更高的热值,本研究对甘蔗渣进行了水热碳化。经过HTC后的废物被称为氢炭,其性质与褐煤相似。在200°C和220°C的三个反应周期(即2、4和6小时)下对原料进行了许多测试。炭的产率随温度和停留时间的增加而降低,而碳率呈上升趋势,在220℃时达到69.1%,反应6h时的热值为24.44 MJ/kg。
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引用次数: 0
A Study on Biologically Active Chalcone Based Benzodiazepines 生物活性查尔酮类苯二氮卓类药物的研究
Pub Date : 2023-05-07 DOI: 10.51611/iars.irj.v12i02.2022.216
Anirudh P. Singh, Anjaneyulu Bendi, Aditi Tiwari
Heterocycles that include nitrogen are now indispensable to humanity. The majority of the major pharmaceuticals on the market are composed of heterocycles that include nitrogen. One such substance is benzodiazepine, which was shown to have potential as an anti-anxiety medication in 1955. A novel class of chalcone-based benzodiazepines continues to receive the most attention because of their enhanced pharmacological, medicinal, and biological actions. The present study covers the chemistry of some important biologically active chalcone-based benzodiazepines.
含氮的杂环现在对人类来说是不可或缺的。市场上的大多数主要药物都是由含氮的杂环化合物组成的。其中一种物质是苯二氮卓类药物,它在1955年被证明具有抗焦虑药物的潜力。一类新型的以查尔酮为基础的苯二氮卓类药物由于其增强的药理学、医学和生物学作用而继续受到最广泛的关注。本研究涵盖了一些重要的生物活性查尔酮基苯二氮卓类药物的化学性质。
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引用次数: 0
Impact of Water Deficit Condition on Osmoregulation of the Brassica Species 亏水条件对芸苔属植物渗透调节的影响
Pub Date : 2023-05-07 DOI: 10.51611/iars.irj.v12i02.2022.214
K. Chandra, Anil Kumar
Oilseed rape and mustard are mostly grown on conserved soil water in the Indian sub-continent. These crops generally suffer from water stress at reproductive period of development. Thus, to obtain higher stable yields of Brassica species under routine stress conditions, it is essential to identify and understand the interactions of different morpho-physiological traits responsible for drought resistance. To explicate interaction of traits related to biochemical, physio-morphological factors for sustaining drought resistance in Brassica species. Dry mass production and partition in a plant is important when increased yield are sought. A osmometer like plant cell which allows only selective solutes to pass through elastic membrane, cell wall and the thin layer of cytoplasm and a vacuole containing an aqueous solution. To express drought tolerance turgidity of cells maintained by osmotic adjustments.
在印度次大陆,油菜和芥菜大多种植在水土保持的土壤上。这些作物在生殖发育时期普遍遭受水分胁迫。因此,为了在常规胁迫条件下获得更高的稳定产量,有必要识别和了解不同形态生理性状对抗旱性的相互作用。目的:探讨芸苔属植物维持抗旱性的生化、生理、形态相关性状的相互作用。在寻求增产时,植物的干批量生产和分区是很重要的。一种类似植物细胞的渗透计,只允许选择性溶质通过弹性膜、细胞壁、细胞质薄层和含有水溶液的液泡。表达通过渗透调节维持的细胞的耐旱性。
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引用次数: 0
Study of Metabolic Syndrome in Pre and Post Menopausal Women 绝经前后妇女代谢综合征的研究
Pub Date : 2023-05-07 DOI: 10.51611/iars.irj.v12i02.2022.211
Meenakshi Singh, J. Aggarwal, S. Tomo, J. Batra, P. Katara
Objective: The goal of this study was to determine the occurrence of metabolic disorder (MS) and its various components among pre-and postmenopausal women and their associated relationship between menopausal status and MS. Materials and methods: The present study was conducted at the Biochemistry department in association with Obstetrics and Gynecology Department, Santosh Medical College and Hospital, Ghaziabad. The necessary approval was obtained from the institutional ethical committee to conduct the study and informed written consent was also obtained from the study subjects. The cross-sectional case-control study included premenopausal females aged between 20-40 years as the control group (n=41) postmenopausal females aged between 50-60 years as the case group (n=41). Results: In the study group (post-menopause women), the mean value of BMI is 26.35±2.302 (kg/m2). In comparison with the control group (pre-menopause women), the mean value of BMI is 24.05±1.851 (kg/m2). There was a statically significant increase in the levels of BMI in the study group in comparison with the control group. There was a statically significant increase in the levels of SBP and DBP in the study group compared with the control group. In the study group, the mean value of FBS is 127.12±48.186 (mg/dl). In comparison with the control group (pre-menopause women), the mean value of FBS is 96.12±25.567 (mg/dl). There was a statically significant increase in the levels of FBS in the study group compared with the control group. Conclusion: It has been concluded that MS was significantly more prevalent among postmenopausal women than premenopausal women. This indicates that they are at risk of developing hypertension, cardiovascular disease, and type 2 diabetes mellitus. Therefore, health care workers should closely monitor for the two conditions as metabolic syndrome is an underlying condition for other non-communicable diseases and also be advised to adopt healthy lifestyles to minimize the incidence of these conditions.
目的:本研究的目的是确定绝经前和绝经后妇女代谢紊乱(MS)的发生及其各组成部分,以及绝经状态与MS之间的相关关系。材料和方法:本研究在Ghaziabad Santosh医学院和医院生物化学系联合妇产科进行。从机构伦理委员会获得必要的批准来进行研究,并从研究受试者那里获得知情的书面同意。横断面病例对照研究选取20 ~ 40岁绝经前女性为对照组(n=41), 50 ~ 60岁绝经后女性为病例组(n=41)。结果:研究组(绝经后妇女)BMI平均值为26.35±2.302 (kg/m2)。与对照组(绝经前妇女)相比,BMI平均值为24.05±1.851 (kg/m2)。与对照组相比,研究组的BMI水平有统计学意义上的显著增加。与对照组相比,研究组的收缩压和舒张压水平有统计学意义的增加。研究组FBS平均值为127.12±48.186 (mg/dl)。与对照组(绝经前妇女)比较,FBS平均值为96.12±25.567 (mg/dl)。与对照组相比,研究组的FBS水平有统计学意义上的显著增加。结论:绝经后妇女的多发性硬化症发生率明显高于绝经前妇女。这表明他们有患高血压、心血管疾病和2型糖尿病的风险。因此,卫生保健工作者应密切监测这两种情况,因为代谢综合征是其他非传染性疾病的潜在疾病,并建议采取健康的生活方式,以尽量减少这些疾病的发病率。
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引用次数: 0
A systematic review on Drug Re-profiling/Re-Purposing 药物重新分析/重新利用的系统综述
Pub Date : 2023-05-07 DOI: 10.51611/iars.irj.v12i02.2022.218
B. Sharma, Dinesh Yadav
Hardcore capability of drug repurposing has allowed rising population of diversified diseased patients to approach various medications with known safety profiles. In an ongoing scenario considering current pharmaceutical market, we have numerous drugs that are approved and repurposed by the U.S. Food and Drug Administration. Developing and bringing a novel drug molecule from the laboratory to a market requires a lot of investment in terms of money, efforts, and time. On the other hand, repurposing a drug holds the capability of bringing out best cures with harmless, ease availability and inexpensive quality. Sildenafil, Chloroquine, Metformin are some examples of repurposed drug used in multiple disease models. Despite numerous challenges, drug repurposing stood to be a core component to any comprehensive drug re-discovering strategies which has been planned to bring benefit to the patients suffering from a wide variety of dreadful ailments. In this review, we have discussed the various repurposed drugs in numerous types of cancer, deadly novel coronavirus (SARS-CoV-2) and some orphan diseases. This paper holds various examples of drugs which are still under clinical trial and have high chances of being approved as repurposed drugs benefitting humankind.
药物再利用的核心能力使越来越多的不同疾病患者能够使用已知安全性的各种药物。考虑到当前的制药市场,我们有许多药物被美国食品和药物管理局批准和重新利用。开发一种新的药物分子并将其从实验室推向市场需要大量的资金、精力和时间投资。另一方面,重新利用一种药物有能力以无害、容易获得和廉价的质量带来最好的治疗方法。西地那非、氯喹、二甲双胍是在多种疾病模型中使用的重新用途药物的一些例子。尽管面临许多挑战,药物再利用仍然是任何综合性药物再发现战略的核心组成部分,这些战略已计划为患有各种可怕疾病的患者带来好处。在这篇综述中,我们讨论了多种类型的癌症,致命的新型冠状病毒(SARS-CoV-2)和一些孤儿疾病的各种重新用途药物。本文列举了一些仍处于临床试验阶段的药物,这些药物很有可能被批准为造福人类的再用途药物。
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引用次数: 0
Synthetic Methods for the formation of Heterocyclic Compounds from Oxime Ether Derivatives 肟醚衍生物形成杂环化合物的合成方法
Pub Date : 2023-05-07 DOI: 10.51611/iars.irj.v12i02.2022.213
Himani Kumari, H. Kumar, K. Sharma
Heterocyclic ring compounds are not only ubiquitous in prime diversity of vital natural products and synthetic pharmaceuticals and thus highly important in organic synthesis. They have an extensive range of applications.  They are mainly used as veterinary products and as agrochemicals. They are also utilized as corrosion inhibitors, sanitizers, antioxidants, dye stuff and as copolymers. They are accustomed as an important source in the synthesis of bioactive organic compounds. Some natural products like antibiotics such as tetracyclines, cephalosporin, penicillin, aminoglycosides, alkaloids such as morphine, vinblastine, atropine, reserpine, tryptamine, reserpine etc. have heterocyclic constituent. Hence, synthesis of heterocyclic compounds from new procedures have been always demanding. Due to wide range of applications of heterocyclic compounds, this study is a survey of literature of last one decade, describing the methods for the heterocyclic ring formation from the oxime ether.
杂环化合物不仅广泛存在于多种重要的天然产物和合成药物中,在有机合成中也具有重要意义。它们有广泛的应用范围。它们主要用作兽药产品和农用化学品。它们也被用作缓蚀剂、杀菌剂、抗氧化剂、染料和共聚物。它们通常是合成生物活性有机化合物的重要来源。一些天然产物如抗生素如四环素、头孢菌素、青霉素、氨基糖苷类,生物碱如吗啡、长春碱、阿托品、利血平、色胺、利血平等都含有杂环成分。因此,从新的方法合成杂环化合物一直要求很高。由于杂环化合物的广泛应用,本文对近十年来的文献进行了综述,介绍了肟醚合成杂环的方法。
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引用次数: 0
SYNTHESIS OF α- HYDROXY-β, γ-UNSATURATED ESTERS α-羟基-β, γ-不饱和酯的合成
Pub Date : 2023-05-07 DOI: 10.51611/iars.irj.v12i02.2022.212
Lokesh Babu Jarugu, Yashwanth D. Vankar, Anita Brar
α-hydroxy-β, γ-unsaturated esters are important building blocks of bioactive compounds, natural products, achiral and chiral vinyl epoxides. These could be easily obtained by isomerization of glycidic esters. In this paper we have reported easy and convenient way of synthesis of α-hydroxy-β, γ-unsaturated esters by isomerisation of glycidic esters using inexpensive catalyst HClO4-SiO2 and eco-friendly ionic liquid. Moderate to good yields with lower reaction times reported.
α-羟基-β, γ-不饱和酯是生物活性化合物、天然产物、非手性和手性环氧乙烯的重要组成部分。这些化合物可以很容易地通过甘油脂异构化得到。本文报道了一种以廉价的HClO4-SiO2催化剂和环保离子液体为原料,由甘油三酯异构化合成α-羟基-β, γ-不饱和酯的简便方法。反应时间较短,产率中等至良好。
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引用次数: 0
Innovations in Teaching - Learning in Higher Educational Institutions in the Current Scenario 当前形势下高校教学创新
Pub Date : 2022-08-29 DOI: 10.51611/iars.irj.v12i01.2022.219
P. Sharmila
The 21st century is an era of creativity and cataclysmic transformation. India has a tremendous need for educated labourers. To enhance the necessary abilities of the teachers and students, the most effective techniques for teaching and learning must be found. To nurture long-lasting and employable abilities, there is a major need to switch pedagogy from fact-based traditional lecture to interactive education. Innovation in education process is now crucial to solving this issue. Adopting the numerous techniques and tactics described in the paper will assist in achieving the goal. The current paper discusses cutting-edge teaching strategies used in the nation's higher education institutions.
21世纪是一个充满创造力和巨变的时代。印度对受过教育的劳动者有着巨大的需求。为了提高教师和学生的必要能力,必须找到最有效的教与学技术。为了培养持久的就业能力,有必要将教学方法从基于事实的传统讲座转变为互动教育。教育过程创新是解决这一问题的关键。采用本文中描述的众多技术和策略将有助于实现这一目标。本文探讨了我国高等教育机构采用的前沿教学策略。
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引用次数: 0
Locating Five Stages of Grief of Dr. Kalanithi 定位卡拉尼蒂医生悲伤的五个阶段
Pub Date : 2022-08-29 DOI: 10.51611/iars.irj.v12i02.2022.200
Shafqat Hussain, Abdul Rauf, Amjad Ali
This study takes place in the realm of psychological literature. It analyzes the autobiography of American Dr. Paul Kalanithi, When Air Biomes Breath. The story revolves around Dr. Kalanithi’s life being a patient of lung cancer at the last stage, IV. The book is marvelous and incredible, life-affirming meditation from this remarkable man, on the subject of difficulty of confronting mortality and the bond between doctor and patient. This is a memoir about his life and disease, combating metastatic lung cancer. He shares grief, suffering, turmoil and psychological trauma and its balance point in the book. Similarly, the researchers have inspected the stages of grief Dr. suffered from. For this, Textual Analysis of the book is conducted through Kubler-Ross Model of grief as a theoretical framework. The study is designed descriptively. The selected excerpts from the story are analyzed to reach the research question. The findings of the study reveal that Dr. Kalanithi had deeply suffered from five stages of grief as proposed by Ross, but his circle of grief goes in contrast. He randomly accepted, rejected, became angry and denied, and again accepted this turmoil. Relatively, this study is helpful for understanding the model and the storyline of Dr. Kalanithi in the realm of psychological literature.
这项研究发生在心理学文学领域。它分析了美国保罗·卡拉尼蒂博士的自传《当空气生物群系呼吸时》。故事围绕着卡拉尼蒂医生作为肺癌晚期患者的生活展开。这本书是了不起的、令人难以置信的、肯定生命的冥想,来自这位杰出的人,主题是面对死亡的困难,以及医生和病人之间的联系。这是一本关于他与转移性肺癌作斗争的生活和疾病的回忆录。他在书中分享了悲伤、痛苦、动荡和心理创伤及其平衡点。同样,研究人员也研究了博士所经历的悲伤阶段。为此,本文以库伯勒-罗斯悲伤模型为理论框架对该书进行了文本分析。本研究采用描述性设计。从故事中选出的片段进行分析,从而得出研究问题。研究结果显示,卡拉尼蒂博士经历了罗斯提出的五个悲伤阶段,但他的悲伤循环与之相反。他随机地接受、拒绝、生气、拒绝,然后再次接受这种混乱。相对而言,本研究有助于理解心理学文献领域中Kalanithi博士的模式和故事情节。
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引用次数: 0
English Language Teaching with Engagement in Mind 关注参与的英语教学
Pub Date : 2022-08-29 DOI: 10.51611/iars.irj.v12i02.2022.204
Lutif Ali Halo
This research studies the post method approaches in the English language teaching context of Pakistan. The study argues that methods are colonial legacy which are imposed upon all the cultural and social settings. The post-method approaches like particularity, practicality and possibility can bring drastic change in English language teaching of Pakistani context. This research has used qualitative questionnaires for collecting data. The selection of research participants is based on purposive sampling. The findings reveal that the post method approach makes teaching and learning effective by emphasizing on the conxtet of the students and situation. Therefore, this study has investigated the post method strategies and approaches practiced in the ELT context of Pakistan.
本研究研究了post - method教学法在巴基斯坦英语教学中的应用。该研究认为,这些方法是强加于所有文化和社会环境的殖民遗产。特殊性、实践性、可能性等后方法教学法可以给巴基斯坦语境下的英语教学带来巨大的变化。本研究采用定性问卷法收集数据。研究参与者的选择是基于有目的的抽样。研究结果表明,岗位教学法通过强调学生的背景和情境,使教与学更加有效。因此,本研究调查了巴基斯坦英语教学背景下的post - method策略和方法。
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引用次数: 0
期刊
IARS' International Research Journal
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