Evaluation of Xiaoaiping Combined with Oxaliplatin and Capecitabine in the Treatment of Advanced Metastatic Gastric Adenocarcinoma

Ye Xu, Zhong-feng Li, M. Meng
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引用次数: 1

Abstract

Objectives: To evaluate the effect of Xiaoaiping combined with oxaliplatin and capecitabine in the treatment of advanced metastatic gastric adenocarcinoma. Methods: Seventy patients with advanced metastatic gastric adenocarcinoma in our hospital from January 2018 to March 2019 were randomly divided into the control group treated with oxaliplatin and capecitabine chemotherapy and the observation group treated with Xiaoaiping. Each group has 35 cases. The short-term efficacy of the two groups was compared. Results: The total effective rate and disease control rate of the observation group were higher than that of the control group. After treatment, tumor markers, vascular endothelial growth factors and inflammatory cytokines were lower than those in the control group. The quality of life score and peripheral lymphocyte subgroup were higher than the control group. The difference was statistically significant (P   0.05). Conclusions: Xiaoaiping combined with oxaliplatin and capecitabine is effective in the treatment of advanced metastatic gastric adenocarcinoma. It's worth popularizing.
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消癌平联合奥沙利铂、卡培他滨治疗晚期转移性胃腺癌的疗效评价
目的:评价消癌平联合奥沙利铂、卡培他滨治疗晚期转移性胃腺癌的疗效。方法:选取2018年1月~ 2019年3月我院收治的晚期转移性胃腺癌患者70例,随机分为对照组和观察组,对照组采用奥沙利铂联合卡培他滨化疗,观察组采用消癌平治疗。每组35例。比较两组近期疗效。结果:观察组总有效率、疾病控制率均高于对照组。治疗后,肿瘤标志物、血管内皮生长因子、炎症因子均低于对照组。生活质量评分和外周血淋巴细胞亚组均高于对照组。差异有统计学意义(p0.05)。结论:消癌平联合奥沙利铂、卡培他滨治疗晚期转移性胃腺癌疗效显著。它值得推广。
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