A Computational Method to Assess Post-operative Risk of Lung Cancer Patients

Kittipat Sriwong, Kittisak Kerdprasop, P. Chuaybamroong, Nittaya Kerdprasop
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Abstract

Abstract—Lung cancer surgery is risky such that sometime patients died after surgery. To reduce loss, we try to create a computational model to anticipate in advance the post-operative survival among the lung cancer patients using statistical and machine learning algorithms. The dataset used in our model building process is data of patients who underwent lung cancer surgery comprising of 470 records with 17 attributes. These data were collected at Wroclaw Thoracic Surgery Centre, Poland during the years 2007 to 2011. For the purpose of validating the built model, we partitioned this dataset into training set and test set with the ratio 70% : 30% and random it 10 times to obtain 10 pairs of training-test set. The training dataset is used as input to build prediction models for the post-operative survival in the lung cancer patients by applying logistic regression and support vector machine (SVM) algorithms. The obtained two models are then compared to choose the best one with the highest predictive performance based on the mean accuracy of the ten iterations. As a result of comparison using test dataset, prediction model built from the logistic regression reaches 82.38% on its average accuracy, while the SVM approach yields 75.67% of its average accuracy.
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评估肺癌患者术后风险的计算方法
肺癌手术是危险的,有时患者在手术后死亡。为了减少损失,我们尝试使用统计学和机器学习算法创建一个计算模型来提前预测肺癌患者的术后生存。模型构建过程中使用的数据集是接受肺癌手术的患者的数据,包括470条记录和17个属性。这些数据于2007年至2011年在波兰弗罗茨瓦夫胸外科中心收集。为了验证所建立的模型,我们将该数据集以70%:30%的比例划分为训练集和测试集,随机10次,得到10对训练-测试集。将训练数据集作为输入,应用logistic回归和支持向量机(SVM)算法建立肺癌患者术后生存预测模型。然后将得到的两个模型进行比较,根据10次迭代的平均精度选择预测性能最高的最佳模型。通过与测试数据集的对比,逻辑回归方法建立的预测模型平均准确率达到82.38%,而支持向量机方法的平均准确率为75.67%。
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