A hybrid microfluidic system for cancer diagnosis based on MEMS biosensors

P. Ortiz, N. Keegan, J. Spoors, J. Hedley, A. Harris, J. Burdess, R. Burnett, T. Velten, M. Biehl, T. Knoll, W. Haberer, M. Solomon, A. Campitelli, C. McNeil
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引用次数: 4

Abstract

A microfluidic system for cancer diagnosis based around a core MEMS biosensor technology is presented in this paper. The principle of the MEMS biosensor is introduced and the functionalisation strategy for cancer marker recognition is described. In addition, the successful packaging and integration of functional MEMS biosensor devices are reported herein. This ongoing work represents one of the first hybrid systems to integrate a PCB packaged silicon MEMS device into a disposable microfluidic cartridge.
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基于MEMS生物传感器的混合微流控癌症诊断系统
提出了一种以MEMS生物传感器技术为核心的癌症诊断微流控系统。介绍了MEMS生物传感器的工作原理,并描述了用于癌症标志物识别的功能化策略。此外,本文还报道了功能性MEMS生物传感器器件的成功封装和集成。这项正在进行的工作是第一个将PCB封装的硅MEMS器件集成到一次性微流控盒中的混合系统之一。
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