[The action of teturam and acetaldehyde on the tissue catecholamines of rats].

Farmakologiia i toksikologiia Pub Date : 1991-11-01
G Kh Bozhko, T P Boĭko, P V Voloshin
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Abstract

The results of the isolated and combined effects of teturam and acetaldehyde indicate that a decrease of noradrenaline levels in the brain and heart is induced by teturam. An increase of adrenaline content in the hypothalamus is determined by acetaldehyde. In the adrenals the agents produce the oppositely directed changes in catecholamine content. Against the background of chronic administration of acetaldehyde teturam potentiates its influence on changes in noradrenaline levels in all tissues except the adrenals and adrenaline levels in the hypothalamus and brain stem.

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[teturam和乙醛对大鼠组织儿茶酚胺的作用]。
teturam和乙醛的分离和联合作用的结果表明,teturam诱导大脑和心脏中去甲肾上腺素水平的降低。下丘脑肾上腺素含量的增加是由乙醛决定的。在肾上腺中,这些药物在儿茶酚胺含量上产生相反方向的变化。在长期给药的背景下,乙醛四乙胺增强了其对除肾上腺和下丘脑和脑干肾上腺素水平外所有组织中去甲肾上腺素水平变化的影响。
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