Formulation and Evaluation of Lime Peel Extract (Citrus aurantiifolia) Gel with Semi-Refined Carrageenan and Glucomannan as Gelling Agent

Shervie Tjitrarukmana
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Abstract

Lime peel extract contains quercetin with sunscreen activity. It could make into gel preparations, which has a transparent semisolid and generally gives a cooling sensation to the skin. A combination of semi-refined carrageenan and glucomannan as a gelling agent can be an alternative to form the strength and elasticity of the gel mass. This study aimed to determine the effect of concentration variations of gelling agents on the physical evaluation of gel preparation results and the optimal formulation for lime peel extract gel as sunscreen. Lime peel extract would make into gel preparation with variations in the concentration of the gelling agent, which are 1%, 1.25%, 1.5%, and 1.75%. Afterward, the physical evaluation included organoleptic, homogeneity, pH, viscosity, spreadability, and adhesion tests. The organoleptic, homogeneity, pH, and adhesion test results show that all formulations meet the requirements. Viscosity test results obtain the best formula III with 3940,00 cPs at 60 rpm . The results of the dispersibility test show the best formulas I and II with 6,10 cm and 5,50 cm. Based on the data analyzed, variations of gelling agents affect the pH, viscosity, spreadability, and adhesion test results. The optimal lime peel extract gel formulation has not defined from the physical evaluation results.
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以半精制卡拉胶和葡甘露聚糖为胶凝剂的酸橙皮提取物凝胶的配方及评价
酸橙皮提取物含有槲皮素,具有防晒活性。它可以制成凝胶制剂,具有透明的半固体,通常给皮肤一种凉爽的感觉。半精制卡拉胶和葡甘露聚糖的组合作为胶凝剂可以替代形成凝胶团块的强度和弹性。本研究旨在确定胶凝剂的浓度变化对凝胶制备效果的物理评价和酸橙皮提取物防晒霜凝胶的最佳配方。酸橙皮提取物在胶凝剂浓度为1%、1.25%、1.5%、1.75%时可制成凝胶制剂。之后,物理评价包括感官、均匀性、pH、粘度、铺展性和粘附性测试。感官、均匀性、pH值和附着力测试结果表明,所有配方均符合要求。粘度测试结果得到最佳配方III,为3940,00cps,转速为60rpm。分散性试验结果表明,配方1和配方2的最佳粒径分别为6、10 cm和5、50 cm。根据分析的数据,胶凝剂的变化会影响pH值、粘度、涂抹性和附着力测试结果。物理评价结果尚未确定最佳酸橙皮提取液凝胶配方。
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