THE EFFECTS OF FRESH GAS FLOW ON CARBOXYHEMOGLOBIN LEVELS IN SMOKERS AND NON-SMOKERS DURING GENERAL ANESTHESIA

Abstract

Introduction: Cigarettes and tobacco, which are used in different ways, are widely used all over the world, despite the known harm to health. Today, the relationship between many diseases and smoking has been shown. Pulmonary complications are the most important cause of mortality and morbidity in the postoperative period, and smoking is one of the most important risk factors for the development of postoperative pulmonary complications. In this study, we aimed to investigate the effect of different fresh gas flows (4 and 6 lt/min) on carboxyhemoglobin levels in smokers and non-smokers who were operated on electively. Methods: A total of 100 patients, aged between 18-80, in the American Society of Anesthesiology risk score I-II risk group, who were scheduled for elective surgery under general anesthesia, were included in the study. Preoperatively, cases were divided into two groups smokers (n = 50) and non-smokers (n = 50). Pre-induction, post-induction, postintubation, intraoperatively every 30 minutes, post-operative, postextubation, postoperative 30th and 60th minutes, peak heart rate, systolic arterial pressure (mmHg), diastolic arterial pressure (mmHg), SpO2, End-tidal carbon dioxide, and carboxyhemoglobin values were measured and recorded. Results: There was no difference between the cases included in the study in terms of gender, age, amount of cigarette smoked, operation time, and extubation time. When compared according to different fresh gas flow rates (n = 25), no statistically significant difference was found between the groups in terms of carboxyhemoglobin values measured at different times before, during, and after the operation. Conclusion: This situation is attributed to the elimination of carboxyhemoglobin from the blood during this period, due to the cessation of smoking in patients scheduled for elective surgery after the preoperative evaluation until the operation.