Design and fabrication of cell adhesion measuring device

Saeed Salehipour, N. Abolfathi, A. Hashemi
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Abstract

Cell adhesion phenomena has an important role on different behavior of cell. Therefore qualitative and quantitative understanding of cell adhesion force is necessary. A low cost micro device has been developed that can demonstrate cell adhesion force against a specific mechanical stimuli. The device that we developed here allows the measuring cell adhesion. This device is made based on poly methyl methacrylate (PMMA). Finally, to test the system functions, we obtained viscoelastic parameters of cell by applying 10 micron displacement that had a good agreement with literature.
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电池黏附测量装置的设计与制造
细胞粘附现象对细胞的不同行为具有重要的影响。因此,对细胞粘附力的定性和定量了解是必要的。一种低成本的微型装置已经开发出来,可以证明细胞对特定机械刺激的粘附力。我们在这里开发的设备可以测量细胞粘附。该装置是由聚甲基丙烯酸甲酯(PMMA)制成的。最后,为了测试系统的功能,我们用10微米的位移得到了细胞的粘弹性参数,与文献吻合较好。
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