PRELIMINARY STUDIES RELATED TO MICROSCOPY AND THE SEDEM EXPERT SYSTEM PROFILE ON FREEZED-DRIED EXTRACT OF LYTHRI HERBA

Valeriu Valeriu Iancu, L. Bucur, Verginica Schröder, M. Apetroaei
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Abstract

"The floral tips of the plant species Lythrum salicaria L. represent a rich source of total polyphenols, among which with the largest share we mention tannins, and this is why this plant material has a standardized monograph in the European Pharmacopoeia 10.0th edition. According to the literature accessed so far, the plant material has antioxidant, anti-inflammatory, hemostatic, antibacterial and antifungal properties, along with modulatory action on carbohydrate metabolism. Powder microscopic examination is an important step in establishing the identity of the plant species used, highlighting elements specific to the aerial part such as spiral vessels of the stem, fragments of the spongy mesophyll with calcium oxalate clusters cells and anomocytic stomata. The application of the SeDeM method on dried plant extracts represents an innovative trend in pharmaceutical technology and contributes to the collection of data in a structured and standardized form. In this paper, the functions and applications of the SeDeM expert system are illustrated upon the freeze-dried extract of Lythri herba for the purpose of easier identification and standardization. Future applications may include obtaining chewable gums or tablets by direct compression."
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赤藓冻干提取物的显微技术及sedem专家系统初步研究
“Lythrum salicaria L.植物的花尖是总多酚的丰富来源,其中我们提到的单宁含量最大,这就是为什么这种植物材料在欧洲药典10.0版中有一个标准化的专著。根据目前查阅的文献,该植物材料具有抗氧化、抗炎、止血、抗菌、抗真菌等特性,并具有调节碳水化合物代谢的作用。粉末显微镜检查是确定所用植物物种身份的重要步骤,突出了空气部分特有的元素,如茎的螺旋血管,海绵状叶肉的碎片,草酸钙簇状细胞和反常细胞气孔。SeDeM方法在干燥植物提取物上的应用代表了制药技术的创新趋势,有助于以结构化和标准化的形式收集数据。本文介绍了SeDeM专家系统在红草冻干提取物鉴定中的功能和应用,以方便鉴定和标准化。未来的应用可能包括通过直接压缩获得可嚼口香糖或药片。”
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