[The effect of streptase in hypoxia on the blood and abdominal aorta in rats].

Farmakologiia i toksikologiia Pub Date : 1991-05-01
A P Pustovalov, I F Voronkov
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引用次数: 0

Abstract

In the experiment of albino rats it was shown that hypobaric hypoxia caused a disorders of hemostasis with destabilization of membranes and imbalance of electrolytes in the erythrocyte-plasma-vessel wall system. Streptase administration in a dose of 2500 U/kg in this case events in some degree the changes in the process of the blood coagulation, viscosity-elasticity properties of erythrocytes, calcium levels in plasma and erythrocytes, sodium and magnium levels in the abdominal aorta wall produced by the "altitude rise" in an altitude chamber.

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[缺氧条件下链酶对大鼠血液及腹主动脉的影响]。
在白化病大鼠的实验中发现,低压缺氧可引起出血障碍,引起细胞膜不稳定和红细胞-血浆-血管壁系统电解质失衡。在这种情况下,2500 U/kg剂量的链酶在一定程度上改变了血液凝固过程、红细胞的粘弹性、血浆和红细胞中的钙水平、腹主动脉壁中钠和镁水平,这些变化是由高原舱中的“海拔上升”引起的。
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