[Glycerol monothioglycolate eczema in a hairdresser. Persistence of the allergen in the hair several weeks after the application of a permanent].

A Reygagne, R Garnier, M L Efthymiou, P Gervais
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Abstract

Glyceryl thioglycolate has been used for a pair of years in acid permanent wave solutions. It appears to be much more sensitizing than ammonium thioglycolate which is usually the main component of this kind of cosmetics. A case of allergic contact dermatitis due to glyceryl thioglycolate is reported. The patient was a 43-year old woman with an eczematous dermatitis of both hands. She was a hairdresser and eczematous eruptions were strictly work-related. She had no direct contact with most cosmetics and only used tools (scissors, clips, pins, rollers, combs...) and hair spray. Patch testing was however done with the standard patch-test screening tray and all the products used in the shop. The only positive reaction was due to a permanent wave solution containing only glyceryl thioglycolate and glycerol. Positive patch-test reactions were also obtained with hair treated with the permanent wave solution and cut immediately or several weeks after the application of the preparation. This observation shows that glyceryl thioglycolate may be responsible for allergic contact dermatitis in hairdressers; it emphasizes the long remanence of the allergen in the hair that makes its eviction specially difficult.

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理发师的单巯基乙酸甘油湿疹。使用永久性发胶几周后,头发中的过敏原仍然存在。
巯基甘油酯已在酸性永久波溶液中使用了两年。它似乎比通常作为这类化妆品主要成分的巯基乙酸铵更致敏。报告一例因巯基甘油酯引起的过敏性接触性皮炎。患者为43岁女性,患有双手湿疹性皮炎。她是一名美发师,湿疹发作完全是与工作有关的。她不直接接触大多数化妆品,只使用工具(剪刀、夹子、别针、卷发棒、梳子……)和发胶。然而,补丁测试是用标准的补丁测试筛选托盘和商店使用的所有产品进行的。唯一的正反应是由于只含有巯基甘油酯和甘油的永久波溶液。用永久波溶液处理头发并立即或在使用该制剂几周后剪掉头发,也可获得阳性的贴片试验反应。这一观察结果表明,巯基甘油酯可能是发型师过敏性接触性皮炎的原因;它强调了过敏原在头发中的长期残留,这使得它的清除特别困难。
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