A case of sultopride poisoning (ingested dose 16 g) in a 35-year-old, 65 Kg man is described. On admission myoclonus, mydriasis, vomiting and cardio-respiratory arrest were observed. Torsades de pointes were treated with potassium chloride infusion and pace maker stimulation. Plasma sultopride concentration was 25 mg/l and urinary concentration 12 g/l. A prolongation of Q-T interval may announce severe arrhythmias in sultopride poisoning.
The Poisons Center located in Bab el Oued University Hospital of Algiers has been opened to the public since January 2, 1991. The staff is made of public health physicians and pharmacists residents trained in toxicology. Phone calls are a new means for obtaining advice on poisonings and the public must be informed on the modalities of use. The number of calls shows that people are willing to use this fast and effective medium. A specific data sheet was created. The analysis of calls includes the origin of call, the nature of products used, the age range the clinical condition of patients, the recommended treatment and the outcome when known.
Acute renal failure and rhabdomyolysis are reported in a 33 year old man who had taken 6 g of amoxapine. Different possible levels for the toxic action of amoxapine are discussed and compared with literature data.
The authors present the results of a study on urinary excretion of caffeine, after a single oral intake of 100 mg of caffeine, in two populations of students at rest and during exercise. Whether expressed in mg/l or mg/g creatinine no significant difference in urinary excretion of caffeine was observed between the two populations and it proves to be lower than the limit level authorized by the IOC (12 mg/l).
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