Analysis and Regulation of the Biotechnical System of the Mechanical Support of Blood Circulation

Abstract

The cardiovascular system (CVS) is a complex and multifunctional system, the control of the parameters of which is a complex task. This study is aimed at solving the problem of analyzing the biotechnical system, consisting of CVS with an univentricular circulation and mechanical circulatory support systems. For this study, a specialized rotary mechanical circulation device was developed. In the course of experimental studies, the hydraulic characteristics of this device were obtained. We studied the biotechnical system at various configurations of the total cavopulmonary connection (TCPC-1, TCPC-2 and TCPC-3) and in the range of impeller rotations of 7000–14000 rpm. Based on the results of this study, we came to the conclusion that the TCPC-3 configuration better normalizes the parameters of the biotechnical system of mechanical circulatory support, and the range of the impeller operation is also determined, at which the system parameters do not exceed the critical level. By maintaining all parameters in a safe physiological range, cardiac output in the CVC with an univentricular circulation is increased by 20%. The results of this work can be used to optimize the control parameters of the circulatory support systems.