In-Vitro Antifungal Efficacy of Zingiber Officinale

S. Iqbal, Urooj Akhtar, Shoaib Siddique
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Abstract

ABSTRACT:Synthetic medicines are being replaced by those derived from natural resources because of cost burden and side effects of synthetic medicines. Zingiber officinale (Ginger) has been act as home remedy against the microbial infections. Its fresh juice has radio protective action that could be helpful in avoiding gamma radiation which exert harmful effects during the period of cancer treatment. It exhibited chemo defensive and antineoplastic action as well as has been useful to cure the inflammation in the body. Present study investigated in vitro antifungal efficacy against Aspergillus niger, Aspergillus oryzaea, Fusarium oxysporum and Fusarium tricinctum using disc diffusion technique. Maximum inhibitory zone against Aspergillus niger produced after 96 hours i.e. 46.66 ±2.5mm and minimum after 48 hours i.e. 41.66 ± 2.5mm. Maximum inhibitory zone against Aspergillus oryzaea was produced after 96 hours i.e. 23.33±1.73 mm and minimum at 48 hours i.e. 17.66 ± 1.73 mm. Maximum inhibitory zone against Fusarium oxysporum was produced after 96 hours i.e. 24.00 ± 1.5mm and minimum at 48 hours i.e. 18.00 ±1.5mm. Maximum inhibitory zone against Fusarium tricinctum was produced after 96 hours i.e. 38.33 ± 2.00 mm and minimum at 48 hours i.e. 35.00 ± 2.00 mm. These concentrates may have been proved to be effective antimicrobials and can be exploited in controlling superfluous microbial growth.
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铁皮姜的体外抗真菌作用
摘要:由于合成药物的成本负担和副作用,合成药物正在被天然资源衍生药物所取代。生姜已被用作治疗微生物感染的家庭药物。它的新鲜果汁具有辐射防护作用,有助于避免在癌症治疗期间产生有害影响的伽马射线。它表现出化学防御和抗肿瘤的作用,并对治疗体内炎症有用。本研究采用圆盘扩散技术研究了其对黑曲霉、米曲霉、尖孢镰刀菌和三角镰刀菌的体外抑菌效果。96小时后对黑曲霉的最大抑菌带为46.66±2.5mm, 48小时后最小抑菌带为41.66±2.5mm。对米曲霉的最大抑菌区为96 h(23.33±1.73 mm),最小抑菌区为48 h(17.66±1.73 mm)。对尖孢镰刀菌的最大抑菌区为96 h(24.00±1.5mm),最小抑菌区为48 h(18.00±1.5mm)。对赤霉病菌的最大抑菌区为96 h(38.33±2.00 mm),最小抑菌区为48 h(35.00±2.00 mm)。这些浓缩物可能已被证明是有效的抗菌剂,可用于控制多余的微生物生长。
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