Effect of Family Psychological Education Program on Positive and Negative Symptoms of Schizophrenic Patients: A Randomized Controlled Trial

Samad Fereidooni, A. Mehryar, Hajjotollah Javidi, R. Afshari
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Abstract

Background: Familial psycho-education is a training model dedicated to providing essential information and educating families with a psychiatric patient to work with mental health professionals as part of a treatment plan for their ill family members. Objectives: Our aim of this study was to investigate the effectiveness of the family psychological didactic program as an adjunctive treatment to medication in hospitalized patients with schizophrenia to reduce negative and positive symptoms. Methods: In this clinical trial, we included 49 Iranian inpatients with a diagnosis of schizophrenia hospitalized at Shiraz Psychiatric Hospital from September 2016 to May 2017. They were randomly assigned to experimental (n = 24) and control (n = 25) groups. All groups were prescribed their usual pharmacological treatments. Additionally, in the experimental group, a psychological education intervention was planned for their families. This intervention consisted of six 90-minute sessions that lasted for three weeks. Before the intervention, after the intervention, and two months after the intervention, all subjects completed the Positive and Negative Syndrome Scale (PANSS). Results: This study was undertaken on 50 hospitalized schizophrenic patients. Most were male (72%). The mean PANSS scores at the pretest and posttest were 82.5 ± 12.594 and 84.72 ± 9.629 for the intervention group and 50.08 ± 11.477 and 51.92 ± 9.823 for the control group, respectively. Based on the ANCOVA, all groups showed the same decrease in the posttest PANSS score, although there was no considerable difference among the groups (F = 0.049; P = 0.825) in the posttest. Nevertheless, eight weeks after the completion of the intervention program, the severity of symptoms was significantly reduced in the intervention group compared to the control group. (F = 165.931; P = 0.001). Conclusions: The family psychological training intervention as an additional treatment for hospitalized patients with schizophrenia can increase the effectiveness of drug treatment. Of course, we must consider the small research sample when generalizing the results.
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家庭心理教育对精神分裂症患者阳性和阴性症状的影响:一项随机对照试验
背景:家庭心理教育是一种培训模式,致力于提供必要的信息,并教育有精神病人的家庭与精神卫生专业人员合作,作为其患病家庭成员治疗计划的一部分。目的:本研究的目的是探讨家庭心理教学计划作为住院精神分裂症患者药物治疗的辅助治疗,以减少阴性和阳性症状的有效性。方法:在这项临床试验中,我们纳入了2016年9月至2017年5月在设拉子精神病院住院的49名确诊为精神分裂症的伊朗住院患者。随机分为试验组(n = 24)和对照组(n = 25)。所有组均给予常规药物治疗。此外,实验组计划对其家庭进行心理教育干预。这项干预包括六个90分钟的疗程,持续三周。在干预前、干预后及干预后2个月,所有被试分别完成阳性和阴性症状量表(PANSS)。结果:本研究以住院精神分裂症患者50例为研究对象。大多数是男性(72%)。干预组PANSS前测和后测的平均分分别为82.5±12.594分和84.72±9.629分,对照组为50.08±11.477分和51.92±9.823分。经ANCOVA分析,各组患者的PANSS评分均出现相同的下降,但组间差异无统计学意义(F = 0.049;P = 0.825)。然而,干预方案完成8周后,干预组的症状严重程度与对照组相比显著降低。(f = 165.931;P = 0.001)。结论:家庭心理训练干预作为精神分裂症住院患者的辅助治疗,可提高药物治疗的有效性。当然,在推广结果时,我们必须考虑到小研究样本。
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