Nasr Yehia, A. Khodairy, Mahmoud Abd El Aleem El-Remailya, K. Aly
{"title":"Synthesis, Characterization, and PASSS Inet Prediction of New Polyesters","authors":"Nasr Yehia, A. Khodairy, Mahmoud Abd El Aleem El-Remailya, K. Aly","doi":"10.21608/sjsci.2022.164408.1033","DOIUrl":null,"url":null,"abstract":"The interfacial polycondensation of indazole monomers 3 and 4 with various aromatic and aliphatic acid chlorides, including isophthaloyl-, terephthaloyl-, adipoyl-, and sebacoyl chloride, gave polyesters 5a-d and 6a-d containing an indazole moiety. The generated polyesters were categorized using elemental analysis, IR, H-NMR, and MS spectra; XRD and Thermal Gravimetry analysis (TGA) examinations. Prediction of inflammatory biological behavior of selected polyesters using PASS Inet at Pa < 0.70, giving a high probability of anti-Gluconate 2-dehydrogenase (acceptor) inhibitor.","PeriodicalId":146413,"journal":{"name":"Sohag Journal of Sciences","volume":"92 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sohag Journal of Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/sjsci.2022.164408.1033","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The interfacial polycondensation of indazole monomers 3 and 4 with various aromatic and aliphatic acid chlorides, including isophthaloyl-, terephthaloyl-, adipoyl-, and sebacoyl chloride, gave polyesters 5a-d and 6a-d containing an indazole moiety. The generated polyesters were categorized using elemental analysis, IR, H-NMR, and MS spectra; XRD and Thermal Gravimetry analysis (TGA) examinations. Prediction of inflammatory biological behavior of selected polyesters using PASS Inet at Pa < 0.70, giving a high probability of anti-Gluconate 2-dehydrogenase (acceptor) inhibitor.
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