Reconfigurable DNA nanostructures for detection of multiple DNA and enzymatic inputs

Susan Buckhout‐White, D. Hastman, C. Person, J. Melinger, M. Ancona, E. Goldman, Igor L. Medintz, Carl W. Brown
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Abstract

The progress within the field of DNA nanotechnology has shown DNA to be an ideal material for the self-assembly of complex two-dimensional and three-dimensional structures. In addition to forming a wide range of structural geometries, DNA has been demonstrated as an exemplary scaffold. In this work we utilize this scaffolding ability to create photonic DNA switches that respond to both DNA and enzymatic inputs and produce complex logic based outputs.
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用于检测多种DNA和酶输入的可重构DNA纳米结构
DNA纳米技术领域的进展表明,DNA是复杂二维和三维结构自组装的理想材料。除了形成广泛的结构几何形状外,DNA已被证明是一种典型的支架。在这项工作中,我们利用这种脚手架能力来创建光子DNA开关,该开关响应DNA和酶的输入,并产生复杂的基于逻辑的输出。
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