Arabidopsis thaliana computationally-generated next-state gene interaction models

Bree Ann LaPointe, D. J. John, J. Norris, Alexandria F. Harkey, Joëlle K. Muhlemann, G. Muday
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Abstract

The construction of gene interaction models must be a fully collaborative and intentional effort. All aspects of the research, such as growing the plants, extracting the mea-surements, refining the measured data, developing the statistical framework, and forming and applying the algorithmic techniques, must lend themselves to repeatable and  sound practices. This paper holistically focuses on the process of producing gene interaction models based on transcript abundance data from Arabidopsis thaliana after stimulation by a plant hormone.
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拟南芥计算生成的下一状态基因相互作用模型
基因相互作用模型的构建必须是一个充分合作和有意的努力。研究的所有方面,如种植植物、提取测量数据、精炼测量数据、开发统计框架以及形成和应用算法技术,都必须适合于可重复和合理的实践。本文全面介绍了拟南芥受植物激素刺激后基于转录丰度数据建立基因相互作用模型的过程。
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