Effects of Alcohol and Tobacco Abuse on Multi-Drug Resistant Tuberculosis Treatment Outcome, Mongolia

Proceedings of the 6th International Conference on Medical and Health Informatics Pub Date : 2022-05-13 DOI:10.1145/3545729.3545793

D. Dashdavaa, N. Dambaa, B. Oidov, Khishigsuren Zuunnast

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Abstract

Abstract: Alcohol and tobacco use, and drug resistance have become key issues in TB care in Mongolia. Although the use of alcohol and tobacco in patients with multi-drug resistant TB (MDR-TB) has been identified, the relationship between MDR-TB treatment outcomes, alcohol and tobacco use has not yet been studied. Aim of study: To study effects of alcohol and tobacco abuse on MDR-TB treatment outcome. Methods: This is randomly assigned case control study. Patients, who enrolled in MDR-TB short regimen between 2020 and 2021, were participated in the study. Alcohol and Nicotine dependence was assessed by Nicotine dependence standard scale and AUDIT scale. Results: Of the 64 MDR-TB patients, 55% were male and the mean age of participants was 38.07±1.75 years. Based on AUDIT, 78% and 22% patients were classified as low risky, harmful, high risk level of alcohol use (Cronbach`s alpha 0.936). Conclusion: Alcohol and tobacco abuse are higher among MDR-TB patients in Mongolia. Alcohol and Nicotine dependence associated with bad treatment outcome of MDR-TB in the country.

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酒精和烟草滥用对多重耐药结核病治疗结果的影响，蒙古

摘要:酒精和烟草使用以及耐药性已成为蒙古结核病治疗的关键问题。虽然已经确定耐多药结核病(MDR-TB)患者使用酒精和烟草，但尚未研究耐多药结核病治疗结果与酒精和烟草使用之间的关系。研究目的:研究酒精和烟草滥用对耐多药结核病治疗结果的影响。方法:采用随机分组病例对照研究。在2020年至2021年期间参加耐多药结核病短期治疗方案的患者参与了这项研究。采用尼古丁依赖标准量表和AUDIT量表对酒精和尼古丁依赖进行评估。结果:64例耐多药结核病患者中，55%为男性，平均年龄为38.07±1.75岁。根据审计，78%和22%的患者被划分为低风险、有害和高风险水平的酒精使用(Cronbach 's alpha 0.936)。结论:蒙古耐多药结核病患者酗酒和吸烟比例较高。在该国，酒精和尼古丁依赖与耐多药结核病治疗结果不良相关。

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Proceedings of the 6th International Conference on Medical and Health Informatics

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