Efficacy and Safety Evaluation of Buyang Huanwu Decoction Combined with Wuling Powder in the Treatment of Deep Vein Thrombosis after Fracture

Kun Ren, Guimei Wei, Yanjie Li, Ruoxing Xing, Hong Cheng
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Abstract

Objective: To explore the effect and safety of Buyang Huanwu Decoction combined with Wuling Powder in the treatment of deep vein thrombosis after fracture. Methods: A total of 76 patients with deep vein thrombosis after fracture were selected as the research object, and the enrollment period was from June 2018 to December 2019. Patients in the reference group were randomly divided into a reference group and a study group. Patients in the reference group were treated with conventional western medicine, and the study group was treated with Buyang Huanwu Decoction combined with Wuling Powder on the basis of conventional Western medicine treatment. The curative effect, adverse reactions and inflammatory factor levels after treatment of patients with deep vein thrombosis after fracture were compared between the two groups. Results: The total effective rate of treatment for patients with deep vein thrombosis after fracture in the study group was 100.00% higher than that of the reference group 86.84%, and the incidence of adverse reactions was 2.63% lower than that of the reference group 18.42%. Inflammatory factors (IL-6, TNF-α, CRP) The level was lower than the reference group, the difference was statistically significant (P<0.05). Conclusion: The development of Buyang Huanwu Decoction combined with Wuling Powder for the treatment of deep vein thrombosis after fracture can effectively improve the clinical treatment effect and medication safety, and improve the level of inflammatory factors.
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补阳还五汤联合五灵散治疗骨折后深静脉血栓的疗效及安全性评价
目的:探讨补阳还五汤联合五灵散治疗骨折后深静脉血栓形成的疗效和安全性。方法:选取76例骨折后深静脉血栓患者作为研究对象,入组时间为2018年6月至2019年12月。参照组患者随机分为参照组和研究组。对照组采用西药常规治疗,研究组在西药常规治疗的基础上加用补阳还五汤联合五灵散治疗。比较两组骨折后深静脉血栓患者治疗后的疗效、不良反应及炎症因子水平。结果:研究组治疗骨折后深静脉血栓患者总有效率比对照组86.84%高100.00%,不良反应发生率比对照组18.42%低2.63%。炎症因子(IL-6、TNF-α、CRP)水平低于对照组,差异有统计学意义(P<0.05)。结论:补阳还五汤联合五灵散治疗骨折后深静脉血栓形成,可有效提高临床治疗效果和用药安全性,提高炎症因子水平。
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