Prevention in Endocrinology

J. Valabhji, R. Agha-Jaffar
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Abstract

Changing epidemiology has led to a clear shift in focus in endocrinology disease prevention. Iodine deficiency disorders and congenital hypothyroidism were examples of conditions, which when left untreated had severe consequences including impaired neurological development. However, introduction of appropriate health policies has successfully increased early recognition and treatment, thereby reducing the associated health burden. The epidemic of type 2 diabetes has now superseded these and presents one of the greatest public health challenges. In some countries, national policies are being implemented to tackle the increasing prevalence with strategies focusing on improving the obesogenic environment, a significant modifiable contributor to type 2 diabetes, as well as strategies that aim to prevent high-risk individuals progressing through to type 2 diabetes, such as the National type 2 diabetes Prevention Programme in England. The potential for prevention in other areas including gestational diabetes, type 1 diabetes, and osteoporosis will also be explored in this chapter.
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内分泌学预防
不断变化的流行病学导致了内分泌疾病预防重点的明显转变。缺碘症和先天性甲状腺功能减退就是这些疾病的例子,如果不加以治疗,会造成严重后果,包括神经发育受损。然而,采取适当的卫生政策成功地增加了早期识别和治疗,从而减少了相关的卫生负担。2型糖尿病的流行现在已经取代了这些,并提出了最大的公共卫生挑战之一。在一些国家,正在实施国家政策,以解决日益增加的患病率,其战略重点是改善致肥环境,这是2型糖尿病的一个重要的可改变因素,以及旨在防止高危人群发展为2型糖尿病的战略,如英国的国家2型糖尿病预防计划。潜在的预防在其他领域,包括妊娠糖尿病,1型糖尿病,骨质疏松症也将探讨在本章。
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