Surgical treatment of ovarian tumors in childhood.

M G Schwöbel, U G Stauffer
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引用次数: 10

Abstract

From 1971 to 1988, 45 girls aged 1 week to 17 years were treated for a total of 46 solid and cystic tumors of the ovaries. Pathohistological examination revealed epithelial tumors in eight cases, a tumor originating from the ovarian stroma in one case, germinal tumors in 17 cases, 15 functional ovarian cysts, and five paraovarian cysts. The stroma tumor and four of the 17 germinal tumors were malignant. Surgical treatment for solid tumors consisted generally of a unilateral salpingo-oophorectomy, but in operations for cystic tumors as well, vital ovarian tissue could only rarely be preserved. Functional ovarian cysts were excised if they were larger than 5 cm. Subsequent to excision of malignant tumors, chemotherapy with cisplatin, vincristine and bleomycin was performed. On follow-up, all patients with benign lesions were well. One of the girls with malignancies died and another is undergoing chemotherapy for tumor recurrence in the contralateral ovary.

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儿童卵巢肿瘤的外科治疗。
从1971年到1988年,45名1周至17岁的女孩接受了总共46例卵巢实体瘤和囊性瘤的治疗。病理组织学检查显示上皮性肿瘤8例,卵巢间质性肿瘤1例,生发性肿瘤17例,卵巢功能性囊肿15例,卵巢旁卵巢囊肿5例。间质瘤和17例生发瘤中的4例为恶性肿瘤。实体瘤的手术治疗通常包括单侧输卵管卵巢切除术,但在囊性肿瘤的手术中,重要的卵巢组织很少能被保留。如果功能性卵巢囊肿大于5cm,则切除。恶性肿瘤切除后,行顺铂、长春新碱、博来霉素联合化疗。随访中,所有良性病变患者均良好。其中一名患有恶性肿瘤的女孩死亡,另一名因对侧卵巢肿瘤复发正在接受化疗。
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