A Physiological Model Of Glucose-insulin Interaction

E. Lehmann, T. Deutsch
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引用次数: 51

Abstract

A physiological model of glucme-insulin interaction in diabetes mellitus has been developed for patient and medical staff education. The model’s predictions also allow a 24 hour simulation of blood glucose profiles to be generated. The model attempts to reflect the underlying @atho)physiology of insulin action and carbohydrate absorption in quantitative terms such as insulin sensitivity, volume of distribution and maximal absorption rate. An overview of the model is presented and its operation illustrated by a case study from a 24 year old insulin-treated diabetic patient.
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葡萄糖-胰岛素相互作用的生理模型
糖尿病中葡萄糖-胰岛素相互作用的生理模型已被开发用于患者和医务人员的教育。该模型的预测还可以生成24小时的血糖谱模拟。该模型试图以胰岛素敏感性、分布体积和最大吸收率等定量术语反映胰岛素作用和碳水化合物吸收的潜在@atho生理学。本文以一位24岁的胰岛素治疗糖尿病患者为例,对该模型进行了概述和操作说明。
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