{"title":"A Physiological Model Of Glucose-insulin Interaction","authors":"E. Lehmann, T. Deutsch","doi":"10.1109/IEMBS.1991.684998","DOIUrl":null,"url":null,"abstract":"A physiological model of glucme-insulin interaction in diabetes mellitus has been developed for patient and medical staff education. The model’s predictions also allow a 24 hour simulation of blood glucose profiles to be generated. The model attempts to reflect the underlying @atho)physiology of insulin action and carbohydrate absorption in quantitative terms such as insulin sensitivity, volume of distribution and maximal absorption rate. An overview of the model is presented and its operation illustrated by a case study from a 24 year old insulin-treated diabetic patient.","PeriodicalId":297811,"journal":{"name":"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13: 1991","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1991-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"51","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13: 1991","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IEMBS.1991.684998","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 51
Abstract
A physiological model of glucme-insulin interaction in diabetes mellitus has been developed for patient and medical staff education. The model’s predictions also allow a 24 hour simulation of blood glucose profiles to be generated. The model attempts to reflect the underlying @atho)physiology of insulin action and carbohydrate absorption in quantitative terms such as insulin sensitivity, volume of distribution and maximal absorption rate. An overview of the model is presented and its operation illustrated by a case study from a 24 year old insulin-treated diabetic patient.