THE EFFECT OF MELON SEEDS FLOUR (Cucumis Melo L.) TOWARD TOTAL CHOLESTEROL LEVEL IN WHITE MALE WISTAR STRAIN RATS (Rattus Norvegicus)

M. Diarti, Erlin Yustin Tatontos, Yunan Jiwintarum, Anggun Sari Mianti
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Abstract

Abstract: Cholesterol is an important element in the body, but in high quantities, it can cause atherosclerosis that will eventually possess an impact on coronary heart disease. One of the foods that can reduce cholesterol is a food contains flavonoids which is found in melon seeds (Cucumis melo l.). It contains high fiber that can reduce either of excessive insulin or blood fat levels. The objective study was to determine the effect of Melon seeds flour Toward Total Cholesterol Level in White Male Wistar Strain Rats. This research was carried out with pre-expriment research design, used One group pretest-postest with 5 male wistar strain rats. Data collected in the form of data examination results of total cholesterol level before and after introducing Melon seeds flour. The mean result of total cholesterol test in white male rats before giving Melon seeds flour was 261 mg / dL, whereas the result of total cholesterol test after giving Melon seeds flour was 190.2 mg/dL. Cholesterol levels decreased by 70.8 mg/dl. In short, presenting Melon seeds flour (Cucumis melo l.) for 14 days can decrease total cholesterol level in white male wistar rats. Keywords: Melon Seeds, wistar strain, total cholesterol.
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瓜子粉的作用白雄性WISTAR大鼠(褐家鼠)总胆固醇水平的研究
摘要:胆固醇是人体中一种重要的元素,但过高的胆固醇会引起动脉粥样硬化,最终对冠心病产生影响。其中一种可以降低胆固醇的食物是一种含有类黄酮的食物,这种类黄酮存在于瓜子中(葫芦瓜)。它含有高纤维,可以降低过量的胰岛素或血脂水平。目的研究瓜子粉对Wistar雄性白鼠总胆固醇水平的影响。本研究采用实验前研究设计,采用1组5只雄性wistar品系大鼠进行前测后测。数据以数据检测的形式采集,采用瓜子粉前后的总胆固醇水平检测结果。白种雄性大鼠给予瓜子粉前的总胆固醇测试平均值为261 mg/dL,给予瓜子粉后的总胆固醇测试平均值为190.2 mg/dL。胆固醇水平降低了70.8毫克/分升。总之,给药14天,瓜子粉(Cucumis melo l.)可以降低白雄性wistar大鼠的总胆固醇水平。关键词:瓜子,wistar菌株,总胆固醇
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