Adaptive Dynamic Analysis-based Optical Coherence Tomography Angiography for Blood Vessel Tail Artifacts Suppression

Junxiong Zhou, Yuntao Li, Jianbo Tang
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Abstract

Optical coherence tomography angiography (OCTA) for blood vessel 3-D structure imaging suffers from blood vessel tail artifacts when using a long decorrelation time (e.g., repeat B-scan acquisition in regular OCTA) or loss of micro vessel signal when using a short decorrelation time. In this work, we developed an adaptive first order field autocorrelation function (g1) analysis-based technique to suppress the tail artifacts under macro vessels while enhancing the dynamic signal of micro vessels. The proposed method is based on the differences of the decorrelation rate and the phase variations of g1 between the vessel voxels and the artifacts regions. A short or a long decorrelation time was applied to obtain the dynamic index of the tail artifacts region or the blood vessel region, respectively. Compared to the post image processing-based techniques, the proposed approach addresses this problem through the physical basis and shows a good performance in suppressing the tail artifacts while enhancing the detection of the micro vessels.
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基于自适应动态分析的光学相干断层血管成像血管尾部伪影抑制
光学相干断层扫描血管成像(OCTA)用于血管三维结构成像,当使用较长的去相关时间(例如,在常规OCTA中重复b扫描采集)或使用较短的去相关时间时,会出现血管尾部伪影或微血管信号丢失。在这项工作中,我们开发了一种基于自适应一阶场自相关函数(g1)分析的技术来抑制宏观血管下的尾部伪影,同时增强微观血管的动态信号。该方法基于血管体素与伪影区域的去相关率和相位变化g1的差异。采用较短或较长的去相关时间分别获得尾部伪影区域和血管区域的动态指标。与基于后图像处理的技术相比,该方法通过物理基础解决了这一问题,在抑制尾部伪影的同时增强了对微血管的检测。
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