A case of sarcoidosis associated with bronchial asthma.

K Ichikawa, M Watanabe, T Takeda, T Miyamoto, A Momose, M Naka, M Usuda, K Yoshizawa, K Hashizume, T Yamada
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Abstract

A 54-year-old woman was treated for bronchial asthma for 14 yr. In March of 1989, chest roentgenography and computed tomography (CT) revealed development of bilateral pulmonary hilar lymph node enlargement. Positive 67Ga uptake was observed in bilateral pulmonary hili. Although levels of serum angiotensin converting enzyme (ACE) and lysozyme were within normal range, biopsy specimen of scalene lymph nodes showed noncaseating epitheloid-cell granuloma, leading to the diagnosis of sarcoidosis. Steroid therapy ameliorated both sarcoidosis and bronchial asthma. Although the association of sarcoidosis and bronchial asthma is uncommon, there may be an etiological relationship between them.

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结节病合并支气管哮喘1例。
一位54岁女性因支气管哮喘接受治疗14年。1989年3月,胸部x线摄影和计算机断层扫描(CT)显示双侧肺门淋巴结肿大。双侧肺hili可见67Ga阳性摄取。虽然血清血管紧张素转换酶(ACE)和溶菌酶水平在正常范围内,但斜角淋巴结活检标本显示非干酪化上皮细胞肉芽肿,诊断为结节病。类固醇治疗可改善结节病和支气管哮喘。虽然结节病与支气管哮喘的关联并不常见,但它们之间可能存在病因学上的关系。
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