Extensive Rhino-Orbital-Cerebral mucormycosis in kidney transplant recipient associated with COVID-19 infection: A Case Report

C. Perera, S. Senanayake
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Abstract

Rhino-orbital-cerebral mucormycosis is an invasive disease caused by fungi. Diabetes mellitus and solid organ transplantation are known risk factors, while it is increasingly recognized in patients with COVID-19 although the exact causal relationship is unknown. Early diagnosis and treatment with liposomal amphotericin B with surgical debridement carries a better outcome in these patients. We present a case of extensive rhino-orbital-cerebral mucormycosis involving the paranasal sinuses, left orbit, cavernous sinus, middle cranial fossa with abscess formation in the left middle cerebellar peduncle in a 46-year-old kidney transplant recipient with concomitant COVID-19 infection.
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肾移植受者与COVID-19感染相关的广泛鼻-眶-脑毛霉菌病1例报告
鼻-眶-脑毛霉病是一种由真菌引起的侵袭性疾病。糖尿病和实体器官移植是已知的危险因素,而在COVID-19患者中越来越多地认识到这一点,尽管确切的因果关系尚不清楚。早期诊断和用两性霉素B脂质体联合手术清创治疗对这些患者有较好的疗效。我们报告一例46岁肾移植受者合并COVID-19感染的广泛鼻-眶-脑毛霉菌病,累及鼻旁窦、左眶、海绵窦、中颅窝并左侧小脑中脚形成脓肿。
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