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Rosai Dorfman disease : A rare association of sero positive rheumatoid arthritis Rosai Dorfman病:一种罕见的血清阳性类风湿关节炎
Pub Date : 2023-08-14 DOI: 10.4038/jmj.v35i1.182
S. Seyon, T. Peranantharajah, J. Nalayini, S. Rushanthini, . Pirannavan
Rosai-Dorfman disease (RDD) is a rare self-limiting histiocytic proliferative disorder that mostly presents with cervical lymphadenopathy with constitutional symptoms. It is associated with connective tissue disease in 10% of cases. Here we present a case of 14-year-old boy who presented with a prolonged fever, arthralgia and generalize lymphadenopathy. Eventually the diagnosis of RDD associated with early Rheumatoid arthritis was made.
罗赛-多夫曼病(RDD)是一种罕见的自限性组织细胞增生性疾病,主要表现为宫颈淋巴结病和体质症状。10%的病例与结缔组织疾病有关。这里我们提出一个14岁的男孩谁提出了一个长期发烧,关节痛和全身淋巴结病。最终诊断为RDD与早期类风湿关节炎相关。
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引用次数: 0
Women empowerment is a tool to improve the quality of life of a community-case study 妇女赋权是改善社区生活质量的一种工具
Pub Date : 2023-08-11 DOI: 10.4038/jmj.v35i1.178
Y. Shanmuganathan, S. Raguraman, S. Kumaran, K. Shiribavan
A reduction in Quality of life (QoL) is evidenced among disempowered populations in Low Middle-Income Countries (LMIC) like Sri Lanka. Women in marginalized populations were culturally identified as potential persons who have care responsibilities to break the vicious cycle of poverty through capacity building. The aim of the study focuses on framework analysis to develop an implementation strategy with women empowerment to enhance the QoL of the community. A study was conducted for 4 years (2018-2022) in the Family Health Center, Kondavil, Northern Province, Sri Lanka, as a qualitative framework analysis using participatory action research methodology. As a result of the study, the empowered women coordinate several health service delivery programs for their community members and financially support their own families. The study can be concluded that women empowerment is an effective tool to improve the QoL of the community.
生活质量(QoL)的下降在斯里兰卡等中低收入国家(LMIC)的无权人群中得到了证明。在文化上,边缘化人口中的妇女被认定为有潜力的人,她们有责任通过能力建设打破贫穷的恶性循环。这项研究的目的是透过框架分析,制定具妇女赋权的实施策略,以提升社区的生活质素。采用参与性行动研究方法,在斯里兰卡北部省康达维尔家庭保健中心进行了为期4年(2018-2022年)的定性框架分析研究。这项研究的结果是,获得权力的妇女为其社区成员协调了几个保健服务提供方案,并在经济上支持了自己的家庭。研究结果显示,妇女赋权是改善社区生活质素的有效工具。
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引用次数: 0
Deaths due to locomotive injuries in Jaffna district- eight-year retrospective study are we prepared to change our attitude? 贾夫纳地区机车伤害造成的死亡——8年回顾性研究我们准备改变态度了吗?
Pub Date : 2023-08-11 DOI: 10.4038/jmj.v35i1.179
U. Mayorathan
Railway-related fatalities were rising and reported throughout the year. Reckless behavior and using the train as a suicide tool are the primary cause of these tragic deaths.A retrospective descriptive study based on decedents of locomotive trauma was carried out at the JMO office, Jaffna, from January 2015 to January 2022.Thirty decedents were included in this study. Among them, twenty-nine were male, and the age of the individuals ranged from 16 to 73 years. Fifty-seven percent(n=17) of them were between 20 to 40 years. Most were married (57%. n=17) and unemployed (57%, n=17). There were 20(67%) accidents, 09(30%) suicides, and manner could not be ascertained in one (03%) death. Among the accidental deaths, 60%(n=12) were due to vehicle-train collisions, and 80%(n=16) of the deaths occurred at railway crossings. Most (67%, n=06) of the suicidal deaths happened alongside the railway track, away from stations, or rail crossings. All the decedents in both accidents (100%, n=20) and suicides (100%, n=09) had lacerations over the head and neck area. Hundred percent (n=20) of accident cases sustained fractures of the head and neck, 33% (n=03) One (10%) case of decapitation was noted in the self-harmed group. Over the chest region, more than 50% of the deaths had fractures in both accidents (80%, n=16) and suicides (56%, n=05). One (10%) case of transection of the body at the level of the chest was seen in a suicide case. Transection of the body at the level of the abdomen was seen in the accident (05%, n=01) and suicide (10%, n=01). The distribution and nature of injuries were almost identical in both upper and lower limbs. The brain is the internal organ that is primarily affected in both accidents (90%, n=19) and suicides (78%, n=07). In eighty percent (n=24) of the cases cause of death has been determined as craniocerebral injuries, while in 20% (n=06) of the cases, multiple injuries were given as the cause of death.The majority of railroad deaths were accidental. Transections of the neck and chest were commoner in suicides than in accidents. The nature of external injuries and internal organ damage were not showing a significant difference in accidents and suicides.
铁路相关的死亡人数全年都在上升。鲁莽的行为和使用火车作为自杀工具是造成这些悲惨死亡的主要原因。2015年1月至2022年1月,在贾夫纳JMO办公室进行了一项基于机车创伤受害者的回顾性描述性研究。本研究包括30名死者。其中男性29例,年龄16 ~ 73岁。其中57% (n=17)的患者年龄在20 - 40岁之间。大多数人已婚(57%)。N =17)和失业(57%,N =17)。事故20例(67%),自杀09例(30%),死亡方式不明1例(03%)。事故死亡中60%(n=12)发生在车列碰撞,80%(n=16)发生在铁路道口。大多数(67%,n=06)自杀死亡发生在铁路轨道旁、远离车站或铁路道口。事故(100%,n=20)和自杀(100%,n=09)的死者头颈部均有撕裂伤。自残组头颈部骨折占100% (n=20),自残组头颈部骨折占33% (n=03),自残组头颈部骨折占10%(1)。在胸部区域,超过50%的死者在事故(80%,n=16)和自杀(56%,n=05)中都有骨折。1例(10%)在自杀病例中看到胸部横断。在事故(05%,n=01)和自杀(10%,n=01)中可见腹部横断。上肢和下肢损伤的分布和性质几乎相同。大脑是主要在事故(90%,n=19)和自杀(78%,n=07)中受到影响的内部器官。在80% (n=24)的病例中,死亡原因被确定为颅脑损伤,而在20% (n=06)的病例中,多重损伤被确定为死亡原因。大多数铁路死亡事故都是意外事故。颈部和胸部横断在自杀中比在事故中更常见。在事故和自杀中,外伤和脏器损伤的性质无显著差异。
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引用次数: 1
Development of human pancreas 人类胰腺的发育
Pub Date : 2023-08-11 DOI: 10.4038/jmj.v35i1.176
R. Niranjan
Pancreas is an exocrine and endocrine organ. Exocrine portion secretes digestive fluid. Endocrine portion secreting insulin and glucagon etc. Pancreas developed from dorsal and ventral pancreatic buds, which arise from either side of distal foregut. When duodenum rotates to right, ventral pancreatic bud(VPB) rotates posterior along with common bile duct(CBD) and finally lies below and behind the dorsal pancreatic bud(DPB). In humans, DPB forms major part and VPB forms inferior part of head and uncinate process of pancreas. Main duct (Duct of Wirsung) is derived from whole of ventral pancreatic duct(VPD) and distal part of dorsal pancreatic duct(DPD). Main duct joins with CBD and it perforated posteromedial side of second part of duodenum at major duodenal papilla. Occasionally accessory duct might originate from proximal part of DPD and open into minor papilla. Sometimes two buds do not fuse and lead to pancreatic divisum. Abnormal rotation and fusion of buds might lead to annular pancreas. A few endodermal pancreatic evaginations may remain and migrate in bowel wall and form accessory(heterotopic) pancreas. Islets originating from DPB have more insulin synthesis. Neck, body and tail of pancreas is supplied by coeliac trunk. Derivatives of right VPB are supplied by branches of superior mesenteric artery. During rotation of VPB, superior mesenteric vessels(SMV) were engaged in between DPB and VPB. Lastly, SMV is located posterior to neck but it is anterior to uncinate process of pancreas. Detailed study of development of exocrine and endocrine portions is required for successful management of pathology of the pancreas.
胰腺是一个外分泌和内分泌器官。外分泌部分分泌消化液。分泌胰岛素、胰高血糖素等的内分泌部分。胰腺由远端前肠两侧的背侧和腹侧胰腺芽发育而来。当十二指肠向右旋转时,腹侧胰芽(VPB)沿胆总管(CBD)后旋,最终位于胰背芽(DPB)的下方和后方。在人类中,DPB是胰腺头和钩突的主要部分,VPB是胰腺头和钩突的次要部分。主胰管(Wirsung胰管)由整个腹侧胰管(VPD)和远端背侧胰管(DPD)组成。主导管与CBD连接,在十二指肠主要乳头处穿透十二指肠第二部分后内侧。偶有副导管起源于DPD近端,并进入小乳头。有时两个芽不融合导致胰腺分裂。芽的异常旋转和融合可能导致环状胰腺。少数胰腺内胚层外溢可在肠壁保留并迁移,形成副胰腺(异位)。来自DPB的胰岛有更多的胰岛素合成。胰腺的颈部、体和尾部由腹腔干供给。右VPB的衍生物由肠系膜上动脉分支供应。在VPB旋转过程中,在DPB和VPB之间的肠系膜上血管(SMV)被占用。最后,SMV位于颈部后方,但位于胰腺钩突前方。胰腺病理的成功管理需要详细研究外分泌和内分泌部分的发展。
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引用次数: 0
Rapid deterioration of a case of anti–N-methyl-D-aspartate receptor encephalitis with an ovarian teratoma, mimicking viral encephalitis 抗n -甲基- d -天冬氨酸受体脑炎伴卵巢畸胎瘤的快速恶化,模拟病毒性脑炎
Pub Date : 2023-08-11 DOI: 10.4038/jmj.v35i1.181
Udeshika Jak, A. Jayakody, M. Lokuhetty, B. Senanayake, S. Kajananan
Anti–N-methyl-D-aspartate receptor (NMDAR) encephalitis has recently emerged as an autoimmune encephalitis syndrome. Younger females are more likely to develop this condition which usually presents as a multistage illness with predominant neuropsychiatric manifestations. It is associated with the neuroglial surface antibodies developing against NMDAR. The association of ovarian teratoma has been well recognised in this condition and tumour resection will intensify the recovery of the illness along with immunotherapy. We present a case of 19-year-old female who presented with acute onset of fever, encephalopathy and facial myorhythmia mimicking acute viral encephalitis. Her clinical status deteriorated within a short period. Later, her CSF became positive for NMDAR antibody and a right ovarian teratoma was detected. Her clinical status markedly improved with immunotherapy and excision of the teratoma following a diagnosis of Anti-NMDAR encephalitis. As a potentially treatable neurological condition, clinicians should be aware of this autoimmune encephalitis syndrome causing encephalitis.
抗n -甲基- d -天冬氨酸受体(NMDAR)脑炎是近年来出现的一种自身免疫性脑炎综合征。年轻女性更有可能发展这种情况,通常表现为以神经精神表现为主的多阶段疾病。它与NMDAR的神经胶质表面抗体有关。卵巢畸胎瘤在这种情况下的相关性已经得到了很好的认识,肿瘤切除将加强疾病的恢复以及免疫治疗。我们提出一个19岁的女性谁提出了急性发作发烧,脑病和面部肌律不齐模仿急性病毒性脑炎。她的临床状况在短时间内恶化。后脑脊液NMDAR抗体阳性,检出右卵巢畸胎瘤。在诊断为抗nmdar脑炎后,通过免疫治疗和畸胎瘤切除,她的临床状况明显改善。作为一种潜在的可治疗的神经系统疾病,临床医生应该意识到这种自身免疫性脑炎综合征引起脑炎。
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引用次数: 0
Epidemiology of acute poisoning among children in urban Sri Lanka: the experience of two tertiary care hospitals in Colombo district 斯里兰卡城市儿童急性中毒的流行病学:科伦坡地区两家三级保健医院的经验
Pub Date : 2023-08-11 DOI: 10.4038/jmj.v35i1.177
K. Dayasiri, V. Thadchanamoorthy, M. Jansz, Senuri Dassanayake, G. Anand
Acute poisoning in children is an important public health problem and one of the leading causes of emergency department admissions following childhood injuries. Although most paediatric ingestions are accidental, children are at a higher risk for serious complications following ingestion of a similar toxic dose compared to adults. The current study evaluated the recent patterns and trends in acute poisoning among children in two tertiary care centers in urban Sri Lanka: Lady Ridge Hospital for Children, Colombo and North Colombo Teaching Hospital, Ragama. Out of 200 cases, the majority were between 1-5 years and male children outnumbered female children. The most common poisons included kerosene oil, paracetamol and “Good Luck” plants. Complication rate was low, and no mortalities were reported. Deliberate poisoning accounted for 1% of total poisonings. The current trends in poisoning among children living in urban Sri Lanka showed decreasing incidence of pesticide poisonings and increasing incidence of pharmaceutical poisonings and poisoning with ornamental plants.
儿童急性中毒是一个重要的公共卫生问题,也是儿童外伤后急诊入院的主要原因之一。虽然大多数儿科摄入是意外的,但与成人相比,儿童在摄入类似毒性剂量后发生严重并发症的风险更高。目前的研究评估了斯里兰卡城市两个三级保健中心的儿童急性中毒的最新模式和趋势:科伦坡的里奇夫人儿童医院和拉加马的北科伦坡教学医院。在200例病例中,大多数在1-5岁之间,男童多于女童。最常见的毒药包括煤油、扑热息痛和“好运”植物。并发症发生率低,无死亡报告。故意中毒占总中毒的1%。目前斯里兰卡城市儿童中毒的趋势表明,农药中毒发生率下降,药物中毒和观赏植物中毒发生率上升。
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引用次数: 0
Docetaxal induced scleroderma like disease 紫杉醇诱导的硬皮病样疾病
Pub Date : 2023-08-11 DOI: 10.4038/jmj.v35i1.183
Sivajini Shanmugalingam, Ushagowry Saravanamuttu, Umagowry Saravanamuttu
Scleroderma like skin disease is a rare entity among the drug induced dermatological manifestations. It is attributed to various drugs and recently to certain oncological medications especially taxanes. Despite being an efficacious chemotherapeutic agent, it results in scleroderma like skin lesions rarely it resolves in some patients if detected early with omission of the culprit drug with or without steroids. Despite its rarity in literature untreated cases develop severe functional limitation due to skin fibrosis. After an exploration of literature search herein we report the first case of docetaxal induced scleroderma in a Sri Lankan which was detected and promptly treated with steroids successfully. We report this case to make clinicians aware about this condition when encountered with a patient having skin fibrosis with background history of chemotherapy, the possibility of a drug induced scleroderma.
硬皮病样皮肤病是一种罕见的药物性皮肤病。它被归因于各种药物,最近被归因于某些肿瘤药物,特别是紫杉烷。尽管它是一种有效的化疗药物,但它会导致硬皮病样的皮肤病变,在一些患者中,如果早期发现遗漏了罪魁祸首药物,有或没有类固醇,它很少会消退。尽管其罕见的文献未经治疗的情况下发展严重的功能限制,由于皮肤纤维化。经过文献检索的探索,我们在此报告第一例紫杉醇诱导硬皮病在斯里兰卡被发现并及时治疗成功的类固醇。我们报告这个病例是为了让临床医生在遇到有化疗背景史的皮肤纤维化患者时意识到这种情况,药物诱发硬皮病的可能性。
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引用次数: 0
Participation in extracurricular activities and associated factors among Jaffna medical students 贾夫纳医学院学生课外活动参与情况及其影响因素
Pub Date : 2023-08-11 DOI: 10.4038/jmj.v35i1.180
T. Mathuvanthi, U. Keerthiga, K. Majure, C. Mahinthan, H. Priyamantha, R. Kumar, G. Sathiadas
Extracurricular activities (ECA) help to nurture the core competencies of a doctor. This study assessed participation in ECA, barriers and attitudes towards participation, and associated sociodemographic and academic factors among medical students of the University of Jaffna.This descriptive cross-sectional study was carried out at the Jaffna Medical Faculty. Stratified random sampling was used ensuring proportionate representation from each batch. Data were collected with a self-administered questionnaire. Frequencies, proportions, and the Chi squared test were used in the analysis with SPSS (v21).In total, 332 students participated (response rate 96.5%); 65.1% reported participating in ECA. Among them 44.9% participated in sports, while 47.2% were involved in cultural/ faith-based activities. The majority participated in ECA on less than 3 days per week (68.1%), and for less than 2 hours per day (61%). Lack of time (27.5%) and transport (24.6%) were key barriers to participation. Many agreed that ECA enabled new friendships (63.2%) and enhanced social skills (60.2%). Ethnicity (p=0.03) and household income (p=0.045) were significantly associated with the level of participation; Sinhala and Muslim students and those with lower income participated at a lower level. Although female students reported lower participation, there was no evidence of an association between gender and ECA participation (p>0.05). Programme phase (p<0.001) and first examination results (p=0.019) were significantly associated with level of participation; students in the para-clinical phase and those who achieved class honours reported a lower level of participation.Over a third of students do not participate in any type of ECA at the Jaffna Medical Faculty. Targeted interventions are needed to improve participation with consideration to the barriers and groups who are less likely to participate in ECA.
课外活动(ECA)有助于培养医生的核心能力。这项研究评估了贾夫纳大学医科学生参加非洲经委会的情况、参与的障碍和态度以及相关的社会人口和学术因素。这项描述性横断面研究是在贾夫纳医学院进行的。采用分层随机抽样,确保每批样本的比例代表性。数据通过自行填写的问卷收集。使用SPSS (v21)进行频率、比例和卡方检验。共有332名学生参与,回复率96.5%;65.1%报告参加了非洲经委会。其中44.9%的人参加体育活动,47.2%的人参加文化/信仰活动。大多数人每周参加ECA少于3天(68.1%),每天少于2小时(61%)。缺乏时间(27.5%)和交通(24.6%)是参与的主要障碍。许多人同意ECA促成了新的友谊(63.2%)和提高了社交技能(60.2%)。种族(p=0.03)和家庭收入(p=0.045)与参与水平显著相关;僧伽罗和穆斯林学生以及低收入学生的参与水平较低。尽管女学生报告的参与度较低,但没有证据表明性别与ECA参与度之间存在关联(p>0.05)。方案阶段(p<0.001)和首次检查结果(p=0.019)与参与水平显著相关;在准临床阶段的学生和那些获得班级荣誉的学生报告了较低的参与水平。在贾夫纳医学院,超过三分之一的学生不参加任何形式的ECA。考虑到障碍和不太可能参加非洲经委会的群体,需要有针对性的干预措施来改善参与。
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引用次数: 0
Right adrenal mematoma causing partial small bowel obstruction in a term neonate 足月新生儿右肾上腺胶质瘤引起部分小肠阻塞
Pub Date : 2023-08-11 DOI: 10.4038/jmj.v35i1.185
H. Sanseevan, S. Manivannan, C. Thagshanaa, S. Gayathri, M. Dayasiri, N. Srisaravanapavathan, M. Nawarathne
Adrenal haematoma in the neonate commonly occurs during the first week of life and usually proceeded by either mechanical trauma or metabolic stresses including hypoxia, hypovolaemia, septicaemia and coagulopathy. Haematomas commonly present with abdominal mass, anemia and hypovolaemia. The authors report a large for gestational age male newborn who presented with partial small bowel obstruction following adrenal haematoma in a background of an otherwise uneventful vaginal delivery. Although this presentation is extremely rare, it is important to timely investigate all sick newborns with presentations which mimic acute surgical abdomen. Accurate diagnosis enables both avoidance of unnecessary surgical explorations and optimal conservative management.
新生儿肾上腺血肿通常发生在出生后的第一周,通常由机械性创伤或代谢应激引起,包括缺氧、低血容量血症、败血症和凝血功能障碍。血肿常伴有腹部肿块、贫血和低血容量。作者报告了一个大胎龄男性新生儿谁提出部分小肠梗阻后肾上腺血肿的背景下,其他平安无事的阴道分娩。虽然这种表现是极其罕见的,重要的是及时调查所有生病的新生儿的表现,模仿急性外科腹部。准确的诊断可以避免不必要的手术探查和最佳的保守治疗。
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引用次数: 0
Intelligent kindness 聪明善良
Pub Date : 2023-08-11 DOI: 10.4038/jmj.v35i1.175
M. G. Sathiadas
No abstract available
没有摘要
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引用次数: 0
期刊
Jaffna Medical Journal
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