[Treatment of liver metastatic ovarian cancer with sequential administration of OK-432 and etoposide].

Nihon Gan Chiryo Gakkai shi Pub Date : 1990-12-20
A Yakabe, T Ito, K Hayashi, S Yamashita, T Ito, N Sugino
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Abstract

OK-432 and etoposide were administered intravenously to a patient with liver metastasis of ovarian cancer. OK-432 induced IFN-gamma and TNF. SuPS and PPD skin reaction became positive after the therapy. The size of metastatic lesions was reduced significantly (partial response). It is suggested that the combination therapy of OK-432 and etoposide may be effective to the liver metastasis of ovarian cancer.

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[序贯给药OK-432和依托泊苷治疗肝转移性卵巢癌]。
OK-432和依托泊苷静脉给药于卵巢癌肝转移患者。OK-432诱导ifn - γ和TNF。治疗后,SuPS和PPD皮肤反应均为阳性。转移灶的大小明显减小(部分缓解)。提示OK-432联合依托泊苷治疗卵巢癌肝转移可能有效。
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[Chemoembolization therapy with lipiodol, cisplatin and etoposide for hepatocellular carcinoma]. [Relationship between human papillomavirus and oncogenes (c-myc, N-myc) amplification in human cervical cancers]. [Treatment of liver metastatic ovarian cancer with sequential administration of OK-432 and etoposide]. Flow cytometric analysis of nuclear DNA content in patients with recurrent epithelial ovarian cancer. [The effect on prognosis and the adverse drug reaction of intermittent cisplatin therapy in advanced ovarian cancer patients].
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