{"title":"Preparation of giant lipobeads using a gel-assisted swelling method","authors":"Zugui Peng, K. Shimba, Y. Miyamoto, T. Yagi","doi":"10.1109/BMEiCON47515.2019.8990310","DOIUrl":null,"url":null,"abstract":"Lipobeads are spherical vesicles of lipid membrane supported by a hydrogel core that hold promise as next-generation biosensors. However, previous methods for generating lipobeads had limitations due to the use of organic solvents and low ionic strength solutions. To overcome these limitations, we developed a method for forming lipobeads by using a gel-assisted swelling approach. Our results show that lipobeads form in osmotic strength solution and supposed to contain no residual organic solvent.","PeriodicalId":213939,"journal":{"name":"2019 12th Biomedical Engineering International Conference (BMEiCON)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2019 12th Biomedical Engineering International Conference (BMEiCON)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/BMEiCON47515.2019.8990310","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Lipobeads are spherical vesicles of lipid membrane supported by a hydrogel core that hold promise as next-generation biosensors. However, previous methods for generating lipobeads had limitations due to the use of organic solvents and low ionic strength solutions. To overcome these limitations, we developed a method for forming lipobeads by using a gel-assisted swelling approach. Our results show that lipobeads form in osmotic strength solution and supposed to contain no residual organic solvent.
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