Air plethysmography characteristic of the pathological segmental hypervolemia of the calf in patients with CVD clinical classes (CEAP)

A. B. Sannikov, E. Shaydakov
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Abstract

Introduction. The involvement of pathological segmental venous hypervolemia of the lower leg in patients with varicose veins in the formation of chronic venous insufficiency (CVI) is an established fact, however, objective criteria for this pathohemodynamic phenomenon have not been definitively determined today.The purpose of the study. Determination by air plethysmography (APG) of the degree of functional disorders in the limb and establishment of significant criteria characterizing pathological segmental hypervolemia of the lower leg in patients with CVD of various clinical classes according to CEAP.Materials and methods. For the period from 2002 to 2019, 380 healthy individuals with no symptoms of chronic venous diseases and 896 patients with CVD were examined with the use of APG, with their distribution in accordance with the CEAR international classification as follows: C0–C1, C2–C3, C4–C6 clinical classes. To assess the intensity of venous blood flow, the following values were calculated: the maximum capacity of the leg veins (Venous Capacity – VC), the volume of their evacuation (Evacuation Volume – EV) for a set time, the maximum venous outflow (Maximum Venous Outflow – MVO), the ratio of these values on both limbs (Venous Capacity Index – VC1, Evacuation Volume Index – EVI, Maximum Venous Outflow Index – MVOI).Results. The most statistically significant and conjugate correlation data were obtained (expectation, mean square deviation, standard error of expectation, median and coefficient of variation) during the analysis in groups according to the characteristic VCI.Discussion. The obtained results allowed us to assert that APG is an informative functional method for diagnosing hemodynamic disorders in patients with lower limb CVD.Conclusion. The established criteria of the venous capacity index will allow in practice to give an objective characterization of the degree of change in hemodynamic disorders in patients with CVD before and after the treatment undertaken.
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CVD临床分型(CEAP)患者小腿病理性节段性高血容量的空气容积图特征
介绍。静脉曲张患者的下肢病理性节段性静脉高血容量参与慢性静脉功能不全(CVI)的形成是一个既定的事实,然而,这种病理血流动力学现象的客观标准目前尚未明确确定。研究的目的。通过空气体积描记仪(APG)测定肢体功能障碍程度,并根据CEAP建立不同临床类型CVD患者下肢病理性节段性高血容量的重要标准。材料和方法。2002 - 2019年,应用APG对380例无慢性静脉疾病症状的健康个体和896例CVD患者进行了检测,其分布符合CEAR国际分类:C0-C1、C2-C3、C4-C6临床分类。为了评估静脉血流量的强度,我们计算了以下数值:在一定时间内腿部静脉的最大容量(venous capacity—VC)、静脉的最大流出量(evacuation volume—EV)、最大静脉流出量(maximum venous outflow—MVO),以及这些数值在四肢上的比值(静脉容量指数—VC1、抽气量指数—EVI、最大静脉流出量指数—MVOI)。在分组分析中,根据特征vci,获得最具统计学意义和共轭相关的数据(期望、均方差、期望标准误差、中位数和变异系数)。结果表明,APG是诊断下肢cvd患者血流动力学障碍的一种信息丰富的功能方法。静脉容量指数的既定标准将允许在实践中给出CVD患者在治疗前后血流动力学障碍变化程度的客观表征。
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