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Multifocal superficial thrombophlebitis of the extremities in HIV infection 艾滋病毒感染引起的四肢多灶性浅表血栓性静脉炎
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-009
P. N. Myshentsev, S. Katorkin
Long-term observations indicate an increased risk of developing venous thromboembolic conditions in people with the human immunodeficiency virus, their tendency to relapse or a widespread nature. In addition, the incidence of thrombosis increases several times in HIV-infected people compared to the average rates characteristic of people of the same age. A clinical case of multiple bilateral lesions of the subcutaneous veins of the upper and lower extremities in a young patient with HIV infection is presented. Ineffective outpatient treatment and ascending superficial thrombophlebitis of the lower extremities required emergency hospitalization and surgical treatment of the patient to prevent thromboembolic complications. In the postoperative period, in order to prevent the progression of the thrombotic process, as well as to relieve the symptoms of an acute inflammatory reaction of the venous wall and paravasal tissues, a complex application of compression therapy, modern oral anticoagulant drugs, phlebotropic drugs with proven efficacy was carried out. The postoperative period proceeded without complications. In the next few days, the patient’s condition improved, there was a clear regression of thrombotic limb damage. Conclusion: In case of multiple thrombotic lesions of the subcutaneous veins of the upper and lower extremities on the background of HIV infection, the combination of timely surgical intervention with systemic anticoagulant therapy and phlebotropic agents of general and topical use has significant effectiveness in the medical rehabilitation of the patient.
长期观察结果表明,人类免疫缺陷病毒感染者患静脉血栓栓塞症的风险增加,而且这种疾病容易复发或具有广泛性。此外,与同龄人的平均发病率相比,艾滋病病毒感染者的血栓形成发病率增加了数倍。本文介绍了一例年轻的艾滋病病毒感染者双侧上下肢皮下静脉多发性病变的临床病例。由于门诊治疗效果不佳和下肢升支性浅表血栓性静脉炎,患者需要紧急住院并接受手术治疗,以防止血栓栓塞并发症的发生。术后,为了防止血栓形成过程继续发展,同时缓解静脉壁和静脉旁组织的急性炎症反应症状,对患者进行了综合应用加压疗法、现代口服抗凝药物和疗效确切的静脉药物治疗。术后没有出现并发症。在接下来的几天里,患者的病情有所好转,血栓性肢体损伤明显消退。结论在艾滋病病毒感染的背景下出现上下肢皮下静脉多发性血栓性病变时,及时进行手术干预,同时进行全身抗凝治疗和一般及局部使用的促血栓形成药物治疗,对患者的医疗康复具有显著效果。
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引用次数: 0
Experience of using homeopathic ointment in the treatment of patients with anal itching 使用顺势疗法软膏治疗肛门瘙痒患者的经验
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-016
L. A. Lichman, S. Katorkin, P. S. Andreev, O. E. Davydova
Introduction. Anal contact or conduction in the anal canal and rectum is a common condition in the coloproctological field, occurring in 5% of the population that affects this country. Treatment consists of hygiene and the use of topical steroids, antibacterial and antifungal agents. No generally accepted attitude towards a private person has been developed.Aim. To study the effectiveness of using homeopathic ointment in the treatment of patients with anal itching.Material and methods. A prospective comparative randomized study was conducted in a specialized advisory center of the Clinics of Samara State Medical University. The study included 96 patients with anal itching without fungal infection of the perianal skin and concomitant purulent pathology. In the main group (n = 46), treatment was carried out using homeopathic ointment in the perianal area 2–3 times a day for 14 days. In the control group (n = 50), treatment was carried out with topical steroid ointments 2–3 times a day for 14 days.Results and discussion. From the data obtained on the use of homeopathic ointment, it follows that it is not inferior in effectiveness to topical steroid ointments in reducing symptoms of the disease (Student’s t-test = 0.35; p > 0.05 and Student’s t-test = 0.28; p > 0.05), and by the number of relapses (χ2 = 0.535; p > 0.05).Conclusion. The use of homeopathic ointment for topical application appears to be a promising new treatment for patients with anal itching and is as effective as topical steroid ointments.
简介肛门接触或肛管和直肠传导是结肠直肠科领域的常见病,我国有 5%的人患有这种疾病。治疗方法包括保持卫生,局部使用类固醇、抗菌剂和抗真菌剂。目前还没有形成普遍接受的个人态度。研究使用顺势疗法软膏治疗肛门瘙痒患者的效果。萨马拉国立医科大学诊所专业咨询中心进行了一项前瞻性随机比较研究。研究对象包括 96 名肛门瘙痒患者,这些患者的肛周皮肤没有真菌感染,也没有并发化脓性病变。主治组(46 人)在肛周使用顺势疗法软膏进行治疗,每天 2-3 次,持续 14 天。对照组(n = 50)则使用外用类固醇软膏进行治疗,每天 2-3 次,连续 14 天。从使用顺势疗法软膏获得的数据来看,在减轻疾病症状(学生 t 检验 = 0.35;P > 0.05 和学生 t 检验 = 0.28;P > 0.05)和复发次数(χ2 = 0.535;P > 0.05)方面,顺势疗法软膏的效果并不逊色于外用类固醇软膏。使用顺势疗法软膏局部涂抹似乎是治疗肛门瘙痒症患者的一种很有前景的新方法,其疗效不亚于外用类固醇软膏。
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引用次数: 0
One-day surgery: treatment of grade 3–4 hemorrhoids in a day patient department 一日手术:在日间病人科治疗 3-4 级痔疮
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-007
M. Burikov, A. G. Kulikov, S. V. Savchenko
Introduction. “One-day surgery” expands the possibilities of providing surgical care in a polyclinic with hospitalization for just one day. This area of medicine allows you to use the most effective method of treating hemorrhoids in a polyclinic – the operation hemorrhoidectomy.Aim. To substantiate the effectiveness of performing hemorrhoidectomy surgery in patients with stage 3–4 hemorrhoids in a day hospital of a polyclinic under the program “One-day surgery” with accelerated recovery of patients.Materials and methods. The main principle for performing hemorrhoidectomy surgery in a day hospital is a careful selection of patients. Closed hemorrhoidectomy with restoration of the anal canal mucosa (by Parks – Milligan – Morgan’s in the second modification of the State Research Center of Coloproctology) under spinal or general anesthesia is the surgery of choice for hemorrhoids treatment in the day patient department of a clinic. 138 surgeries were performed in the day patient department during 2 years and 10 months. After surgery, patients were placed in the surgical day-patient department wards for 3–5 hours until full activation. Then they were allowed to go home without being accompanied by a medical worker. The satisfaction of patients with the program was analyzed by a survey with a 5-point scale.Results. The timing of scheduled operations for patients has been shortened. The number of complications after hemorrhoidectomy in the early postoperative period was decreased, without long-term postoperative complications. The treatment of such patients in the surgical day-patient department demonstrated a good economic effect. The overall satisfaction with the one-day surgery program was very high (4.82). The results confirmed the effectiveness of this area of medicine.Discussion. Our experience of performing hemorrhoidectomy operations in a day surgical hospital for 3 years confirms the existence of a number of advantages over treating patients in a 24-hour hospital.Conclusions. The “One-day Surgery” and accelerated patient recovery programs expand the possibilities for treating patients with stage 4 hemorrhoids directly in the polyclinic, and thus reduce the burden on the surgical hospital.
导言"单日手术 "扩大了在综合诊所提供手术治疗的可能性,只需住院一天。在这一医学领域,您可以在综合医院使用治疗痔疮最有效的方法--痔切除手术。证实在综合医院的日间医院根据 "一日手术 "方案对 3-4 期痔疮患者实施痔切除手术的有效性,并加速患者的康复。在日间医院进行痔疮切除手术的主要原则是谨慎选择患者。在脊髓麻醉或全身麻醉下进行闭合性痔疮切除术并恢复肛管粘膜(根据国家结肠直肠病学研究中心第二次修改中的 Parks - Milligan - Morgan's 方法)是诊所日间病人科治疗痔疮的首选手术。在两年零十个月的时间里,日间病人科共进行了 138 例手术。手术后,患者被安置在日间手术部病房3-5个小时,直到完全康复。然后,他们可以在没有医务人员陪同的情况下回家。通过一项 5 分制调查分析了患者对该计划的满意度。患者预定手术的时间缩短了。术后早期痔疮切除术后并发症的数量减少了,术后长期并发症也没有出现。在日间手术部治疗此类患者显示出良好的经济效益。一日手术项目的总体满意度非常高(4.82)。结果证实了这一医学领域的有效性。我们在日间手术医院开展痔疮切除手术已有 3 年时间,经验证明,与 24 小时医院相比,日间手术具有很多优势。结论:"一日手术 "和加速患者康复计划扩大了在综合诊所直接治疗 4 期痔疮患者的可能性,从而减轻了外科医院的负担。
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引用次数: 0
Biological therapy of bariatric surgery complications 减肥手术并发症的生物治疗
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-011
A. Khitaryan, A. Mezhunts, K. S. Oplimakh, A. Orekhov, D. Melnikov, S. A. Adizov, V. N. Kislyakov, A. A. Abovyan
In recent years, the number of performed bariatric interventions has increased significantly. Despite the high effectiveness of this method of treatment, the occurrence of complications is not uncommon. The most common complications are stapler line leaks, occurring in 1.5–2.4% of cases; anastomotic leakage after One Anastomosis Gastric Bypass – in 2.2–8% of cases. The problem with all methods is the increased duration of treatment and the need to go without food for significant periods of time, which means starting parenteral nutrition and risking malnutrition. The article demonstrates the effectiveness of biological therapy for complications of bariatric surgery in a series of clinical cases. Clinical cases of 2 patients with anastomotic leakage after One Anastomosis Gastric Bypass are described; also 2 patients with incompetent staple line after laparoscopic Sleeve Gastrectomy. PRP therapy, stromal vascular fraction (SVF) and fibrin glue were used. Platelet-rich plasma is an autologous blood serum containing high concentrations of platelets and growth factors. As a result, after 4 courses of PRP therapy, the patient with the failure of the upper third of the stapler line received an application of twocomponent fibrin glue “Kriofit” with a positive effect. In addition, positive dynamics was observed in the patient with the use of threecomponent therapy of anastomotic leakage. Based on the above facts, it can be concluded, that biological therapy demonstrates great potential value in the treatment of bariatric surgery complications such as stapler line leaks, and anastomotic leakage.
近年来,实施减肥手术的数量大幅增加。尽管这种治疗方法非常有效,但并发症的发生并不少见。最常见的并发症是缝合线渗漏,发生率为 1.5-2.4%;单吻合胃旁路术后吻合口渗漏--发生率为 2.2-8% 。所有方法的问题都在于治疗时间延长,需要长时间不进食,这就意味着要开始肠外营养,面临营养不良的风险。文章通过一系列临床病例证明了生物疗法对减肥手术并发症的有效性。文章描述了 2 例单次吻合胃旁路术后吻合口漏的患者的临床病例,以及 2 例腹腔镜袖带胃切除术后缝合线失效的患者的临床病例。采用了富血小板血浆疗法、基质血管成分(SVF)和纤维蛋白胶。富血小板血浆是一种自体血清,含有高浓度的血小板和生长因子。结果,经过 4 个疗程的富血小板血浆治疗后,订书机线上部三分之一失败的患者接受了双组分纤维蛋白胶 "Kriofit "的应用,并取得了积极的效果。此外,使用三组份疗法治疗吻合口渗漏的患者也观察到了积极的动态效果。基于上述事实,可以得出结论,生物疗法在治疗减肥手术并发症(如缝合线渗漏和吻合口渗漏)方面具有巨大的潜在价值。
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引用次数: 0
Is it safe to discontinue anticoagulant after surgical treatment of varicose vein disease, which caused pulmonary embolism? 手术治疗导致肺栓塞的静脉曲张疾病后停用抗凝剂是否安全?
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-005
T. G. Kipiani, V. V. Kozlova, K. Lobastov
Superficial vein thrombosis, which is mostly caused by lower extremity varicose vein disease, can be complicated by pulmonary embolism. At the same time, the optimal duration of anticoagulant therapy for pulmonary embolism originated from varicose vein thrombosis is still under debate. On the one hand, the presence of varicose veins is considered a small risk factor for the development of venous thromboembolic events, which persistence determines an increased risk of relapse and requires prolonged anticoagulant therapy. On the other hand, elimination of varicose veins is associated with reduced risk of subsequent venous thromboembolic events. The article describes a clinical case of recurrent pulmonary embolism after surgical treatment of varicose vein disease, which caused primary pulmonary embolism. A 45-year-old patient suffering from left lower extremity varicose vein disease for 5 years was admitted to the intensive care unit with suspected pulmonary embolism. The further examination revealed signs of thrombotic occlusion of the segmental and subsegmental branches of the pulmonary arteries bilaterally and the middle lobe branch of the right pulmonary artery, as well as signs of the right-sided heart overload. In this case, pulmonary embolism was found to originate from thrombosis of the trunk of the great saphenous vein ofthe left lower extremity with a proximal border at the level of the lower leg. No signs of deep vein involvement were detected. The parenteral anticoagulant therapy initiated in the hospital was followed by switching to therapeutic doses of rivaroxaban. The signs of recanalization of involved veins were identified after 6 months of treatment, and it was decided to perform endovenous laser coagulation of the trunk of the great saphenous vein combined with mini-phlebectomy of varicose tributaries on continuous oral anticoagulant therapy. The rivaroxaban therapy was completed a month after intervention. However, 7 days later the patient was diagnosed with repeated symptomatic pulmonary embolism, which originated from thrombosis of the left popliteal vein. It was recommended to resume anticoagulant therapy of indefinite duration. The article discusses the issues of optimal duration of treatment for pulmonary embolism originated from thrombosis of superficial varicose veins, as well as the possible timing of completion of anticoagulant therapy after the intervention.
浅静脉血栓大多由下肢静脉曲张疾病引起,可并发肺栓塞。同时,对于静脉曲张血栓引起的肺栓塞,抗凝治疗的最佳持续时间仍存在争议。一方面,静脉曲张的存在被认为是发生静脉血栓栓塞事件的一个小风险因素,而静脉曲张的持续存在决定了复发风险的增加,需要长时间的抗凝治疗。另一方面,静脉曲张的消除与随后发生静脉血栓栓塞事件的风险降低有关。文章描述了一例因手术治疗静脉曲张疾病而导致原发性肺栓塞后复发肺栓塞的临床病例。一名 45 岁的患者患有左下肢静脉曲张疾病 5 年,因怀疑肺栓塞被送入重症监护室。进一步检查发现,双侧肺动脉节段和节段下分支以及右肺动脉中叶分支均有血栓闭塞的迹象,同时还有右侧心脏负荷过重的迹象。在该病例中,发现肺栓塞源于左下肢大隐静脉主干的血栓形成,其近端边界位于小腿水平。没有发现深静脉受累的迹象。在医院开始接受肠外抗凝治疗后,转为服用治疗剂量的利伐沙班。治疗 6 个月后,发现受累静脉有再通迹象,于是决定对大隐静脉主干进行静脉腔内激光凝固术,并在持续口服抗凝药的基础上对曲张支流进行小静脉切除术。利伐沙班治疗在介入治疗一个月后结束。然而,7 天后,患者被诊断为反复出现症状性肺栓塞,源于左侧腘静脉血栓形成。建议恢复无限期抗凝治疗。文章讨论了浅静脉曲张血栓形成所致肺栓塞的最佳治疗时间问题,以及介入治疗后完成抗凝治疗的可能时机。
{"title":"Is it safe to discontinue anticoagulant after surgical treatment of varicose vein disease, which caused pulmonary embolism?","authors":"T. G. Kipiani, V. V. Kozlova, K. Lobastov","doi":"10.21518/akh2024-005","DOIUrl":"https://doi.org/10.21518/akh2024-005","url":null,"abstract":"Superficial vein thrombosis, which is mostly caused by lower extremity varicose vein disease, can be complicated by pulmonary embolism. At the same time, the optimal duration of anticoagulant therapy for pulmonary embolism originated from varicose vein thrombosis is still under debate. On the one hand, the presence of varicose veins is considered a small risk factor for the development of venous thromboembolic events, which persistence determines an increased risk of relapse and requires prolonged anticoagulant therapy. On the other hand, elimination of varicose veins is associated with reduced risk of subsequent venous thromboembolic events. The article describes a clinical case of recurrent pulmonary embolism after surgical treatment of varicose vein disease, which caused primary pulmonary embolism. A 45-year-old patient suffering from left lower extremity varicose vein disease for 5 years was admitted to the intensive care unit with suspected pulmonary embolism. The further examination revealed signs of thrombotic occlusion of the segmental and subsegmental branches of the pulmonary arteries bilaterally and the middle lobe branch of the right pulmonary artery, as well as signs of the right-sided heart overload. In this case, pulmonary embolism was found to originate from thrombosis of the trunk of the great saphenous vein ofthe left lower extremity with a proximal border at the level of the lower leg. No signs of deep vein involvement were detected. The parenteral anticoagulant therapy initiated in the hospital was followed by switching to therapeutic doses of rivaroxaban. The signs of recanalization of involved veins were identified after 6 months of treatment, and it was decided to perform endovenous laser coagulation of the trunk of the great saphenous vein combined with mini-phlebectomy of varicose tributaries on continuous oral anticoagulant therapy. The rivaroxaban therapy was completed a month after intervention. However, 7 days later the patient was diagnosed with repeated symptomatic pulmonary embolism, which originated from thrombosis of the left popliteal vein. It was recommended to resume anticoagulant therapy of indefinite duration. The article discusses the issues of optimal duration of treatment for pulmonary embolism originated from thrombosis of superficial varicose veins, as well as the possible timing of completion of anticoagulant therapy after the intervention.","PeriodicalId":398195,"journal":{"name":"Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)","volume":"6 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141126789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Local therapy in the postoperative management of patients with lower limb varicose vein disease 下肢静脉曲张患者术后治疗中的局部疗法
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-008
I. N. Mokhamad
Introduction. Varicose veins of the lower extremities are one of the most common diseases, affecting 20 to 40% of the population. One of the most common treatment methods is endovenous laser coagulation (EVLC).Aim. To evaluate the effectiveness of local gel therapy based on escin, heparin and essential phospholipids in the postoperative administration of patients after endovenous laser coagulation.Materials and methods. A complex treatment of 53 patients with varicose veins of the lower extremities of classes C2-C3 according to the CEAP nomenclature was carried out. Patients were divided into 2 statically homogeneous groups with an equal number. All patients underwent endovenous laser obliteration of the trunk of the great saphenous vein in combination with miniphlebectomy of tributaries on the thigh and lower leg.Results. In both groups, the largest number were patients with incompetence of the GSV trunk up to the border in /3 and c/3 of the lower leg, with further discharge along the tributaries of the GSV along the medial surface of the lower leg. The failure of the GSV trunk to the level of the knee joint gap was accompanied by the presence of varicose-transformed tributaries along the anterior surface of the thigh, in the area of the knee joint. The addition of Detragel led to the relief of phlebitis and hematomas, a pronounced decrease in pain and edematous syndrome.Discussion. Transdermal drug delivery has great promise as an alternative to oral and intravenous treatment, especially for patients suffering from chronic diseases. The three-component composition allows you to influence all parts of the pathogenesis of the disease.Conclusion. The data obtained on the use of local gel therapy based on escin, heparin and essential phospholipids after EVLO of the GSV indicate the need for local therapy to improve the quality of life of patients, their rapid rehabilitation and improve immediate and long-term results.
简介下肢静脉曲张是最常见的疾病之一,影响着 20% 至 40% 的人口。最常见的治疗方法之一是静脉腔内激光凝固术(EVLC)。评估静脉腔内激光凝固术后患者术后使用基于埃辛、肝素和必需磷脂的局部凝胶疗法的效果。根据 CEAP 术语,对 53 名 C2-C3 级下肢静脉曲张患者进行了综合治疗。患者被分为两组,每组人数相同。所有患者都接受了大隐静脉主干的静脉腔内激光湮灭术,同时对大腿和小腿的支流进行了微静脉切除术。在两组患者中,最多的患者是大隐静脉主干至小腿/3和c/3处边界不通,沿着大隐静脉支流进一步沿小腿内侧表面排出。GSV 主干在膝关节间隙处出现衰竭,同时在膝关节区域的大腿前表面出现曲张变形的支流。加入Detragel后,静脉炎和血肿得到缓解,疼痛和水肿综合征明显减轻。透皮给药作为口服和静脉注射治疗的替代疗法大有可为,尤其是对于慢性病患者。三组份成分可以影响疾病发病机制的各个环节。在 GSV EVLO 后使用以 escin、肝素和必需磷脂为基础的局部凝胶疗法所获得的数据表明,有必要使用局部疗法来改善患者的生活质量,使其快速康复,并提高近期和远期疗效。
{"title":"Local therapy in the postoperative management of patients with lower limb varicose vein disease","authors":"I. N. Mokhamad","doi":"10.21518/akh2024-008","DOIUrl":"https://doi.org/10.21518/akh2024-008","url":null,"abstract":"Introduction. Varicose veins of the lower extremities are one of the most common diseases, affecting 20 to 40% of the population. One of the most common treatment methods is endovenous laser coagulation (EVLC).Aim. To evaluate the effectiveness of local gel therapy based on escin, heparin and essential phospholipids in the postoperative administration of patients after endovenous laser coagulation.Materials and methods. A complex treatment of 53 patients with varicose veins of the lower extremities of classes C2-C3 according to the CEAP nomenclature was carried out. Patients were divided into 2 statically homogeneous groups with an equal number. All patients underwent endovenous laser obliteration of the trunk of the great saphenous vein in combination with miniphlebectomy of tributaries on the thigh and lower leg.Results. In both groups, the largest number were patients with incompetence of the GSV trunk up to the border in /3 and c/3 of the lower leg, with further discharge along the tributaries of the GSV along the medial surface of the lower leg. The failure of the GSV trunk to the level of the knee joint gap was accompanied by the presence of varicose-transformed tributaries along the anterior surface of the thigh, in the area of the knee joint. The addition of Detragel led to the relief of phlebitis and hematomas, a pronounced decrease in pain and edematous syndrome.Discussion. Transdermal drug delivery has great promise as an alternative to oral and intravenous treatment, especially for patients suffering from chronic diseases. The three-component composition allows you to influence all parts of the pathogenesis of the disease.Conclusion. The data obtained on the use of local gel therapy based on escin, heparin and essential phospholipids after EVLO of the GSV indicate the need for local therapy to improve the quality of life of patients, their rapid rehabilitation and improve immediate and long-term results.","PeriodicalId":398195,"journal":{"name":"Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141127110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combined use of oral and topical forms of phlebotonics after endovasal laser coagulation 在血管内激光凝固术后联合使用口服和外敷两种形式的止血药
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-010
Yu. M. Chubirko, I. O. Kasyanov
Introduction. The combination of endovasal laser coagulation and miniphlebectomy is actively used in the treatment of Chronic venous diseases, however, the question of improving the management of such patients in the postoperative period remains actual.Aim. To evaluate the effectiveness of the combined use of oral and topical forms of phlebotonics after endovasal laser coagulation.Materials and methods. The study was conducted in 60 patients after surgery divided into 2 comparable (n = 30). The group 1 was treated with MPFF 1000 mg (Detralex) once a day during the perioperative period (10 days before surgery and up to 2 months after) and additionally topical Detragel daily 3 times a day for 10 days after the intervention. The group 2 used heparin topical form for 10 days after surgery. Control was carried out on the 1st day, 10th day after surgery, as well as after 3 and 6 months.Results. In group 1, there was a statistically more significant decrease in the level of pain on days 1 and 10 after surgery (p ≤ 0.05), while the frequency of hyperpigmentation at months 3 and 6 after surgery was also less presented.Conclusions. The combination of endovasal laser coagulation and miniphlebectomy while taking MPFF and a gel based on heparin, escin and essential phospholipids is accompanied by less severe pain and the level of hyperpigmentation in the postoperative period.
导言。腔内激光凝固术和微型静脉切除术的联合应用在慢性静脉疾病的治疗中得到了积极的应用,然而,如何改善此类患者术后的管理仍是一个实际问题。评估腔内激光凝固术后联合使用口服和外用止血药的效果。研究对象为 60 名术后患者,分为 2 组(n = 30)。第一组在围手术期(术前 10 天和术后 2 个月内)每天一次使用 MPFF 1000 毫克(Detralex),并在干预后的 10 天内每天三次外用 Detragel。第 2 组在术后 10 天内使用肝素外用制剂。在术后第 1 天、第 10 天以及 3 个月和 6 个月后进行对照。在第1组中,术后第1天和第10天的疼痛程度有更明显的统计学下降(P≤0.05),而术后第3个月和第6个月出现色素沉着的频率也较低。在服用 MPFF 和基于肝素、埃丝菌素和必需磷脂的凝胶的同时进行血管内激光凝固术和迷你静脉切除术,术后疼痛和色素沉着的程度较轻。
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引用次数: 0
Methods of preventing surgical site infections 预防手术部位感染的方法
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-013
A. Morozov, A. Sergeev, V. Chervinets, J. V. Chervinets, O. N. Guskova, O. N. Skaryakina, E. N. Egorova
Healthcare-associated infections are the most common and relevant to all healthcare facilities of all types. Surgical site infections are the most frequently reported type of healthcare-associated infections. Surgical site infections are also one of the main causes of prolonged hospital stays, prolonged antibiotic therapy, unplanned re-hospitalizations, worsened long-term patient outcomes and the prescription of additional surgical interventions. At present, it is prevention that has been identified as the single most important strategy to combat surgical site infection. The proposed three-stage model combines perioperative interventions as well as interdisciplinary collaboration to continuously improve the quality of care. This approach includes preoperative, intraoperative, and postoperative prevention methods. Current preoperative strategies for the prevention of surgical site infections can significantly reduce the risk of developing this nosology; one important aspect of preoperative prophylaxis includes the identification, elimination, and/or correction of modifiable as well as non-modifiable risk factors. In addition, it is possible to identify intraoperative risk factors, of which the duration of surgical intervention is fundamentally important. Postoperative risk factors include hyperglycemia and diabetes mellitus, postoperative wound care and blood transfusion. Many effective ways of preventing surgical site infections have been developed, which include separate methods of preoperative, intraoperative and postoperative prophylaxis, however, only through the implementation of a comprehensive model that combines all perioperative measures, health care institutions will be able to effectively reduce the incidence of healthcare-associated infections and improve patient outcomes. Despite the fact that currently there is an active development of new methods of surgical site infections prophylaxis, the direct implementation of these technologies in the practical activity of specialists is of primary importance.
医疗保健相关感染是最常见的,与所有类型的医疗保健机构都息息相关。手术部位感染是最常报告的医疗相关感染类型。手术部位感染也是导致住院时间延长、抗生素治疗时间延长、非计划性再次住院、患者长期预后恶化以及开具额外手术干预处方的主要原因之一。目前,预防已被确定为抗击手术部位感染的最重要策略。建议的三阶段模式结合了围手术期干预措施和跨学科合作,以不断提高护理质量。这种方法包括术前、术中和术后预防方法。目前预防手术部位感染的术前策略可以大大降低发生这种疾病的风险;术前预防的一个重要方面包括识别、消除和/或纠正可改变和不可改变的风险因素。此外,还可以识别术中风险因素,其中手术干预的持续时间至关重要。术后风险因素包括高血糖和糖尿病、术后伤口护理和输血。目前已开发出许多预防手术部位感染的有效方法,包括术前、术中和术后预防的不同方法,但只有通过实施一种综合模式,将所有围手术期措施结合起来,医疗机构才能有效降低医疗相关感染的发生率,改善患者的预后。尽管目前正在积极开发预防手术部位感染的新方法,但将这些技术直接应用于专科医生的实践活动才是最重要的。
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引用次数: 0
Supportive local treatment of diseases of the distal colon of various inflammatory genesis in the outpatient department 在门诊部对各种炎症引起的远端结肠疾病进行局部辅助治疗
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-003
B. M. Belik, A. N. Kovalev, Ya. B. Mirkin, M. E. Ponomarenko, A. A. Kryachko, V. V. Skorlyakov, V. F. Babiev, A. Kivva
Introduction. Currently, along with the improvement of the scheme of combined drug therapy with first-line anti-inflammatory drugs, important importance is attached to adjuvant topical methods of treating diseases of the distal colon of various inflammatory genesis.Aim. Evaluate the clinical efficacy of the drug on sodium hyaluronate as an adjuvant topical agent in the complex treatment of patients with diseases of the distal colon.Materials and methods. A comparative analysis of the results of drug treatment of 97 patients with diseases of the distal colon of various inflammatory genesis, which were divided into two groups, was carried out. In 46 (47.4%) patients of the I (control) group, standard drug therapy with basic anti-inflammatory drugs was performed; 51 (52.6%) patients – II (main) group, the standard program of drug treatment was supplemented with instillations into the rectum of the drug on sodium hyaluronate (0.8 mg of hyaluronic acid in 1 ml). The comparative assessment of the results of treatment took into account the severity of clinical, laboratory and endoscopic manifestations of the disease.Results. In patients of the main group, there was a significant reduction in the healing time of erosions and ulceration of the mucous membrane of the distal colon compared with patients in the control group (29.4 ± 5.7 days, respectively, versus 52.8 ± 6.2 days). Also, in patients of the main group, it was possible to achieve stable clinical and laboratory remission of the disease at an earlier time, restoration of patients’ ability to work, and improvement of their quality of life.Conclusion. The results obtained by us allow us to recommend the drug on sodium hyaluronate as an additional topical drug for the medical treatment of chronic diseases of the distal colon of various inflammatory genesis in outpatient settings.
导言。目前,随着一线抗炎药物联合用药治疗方案的完善,治疗结肠远端各种炎症性疾病的辅助局部用药方法受到重视。评价透明质酸钠作为辅助外用药物在结肠远端疾病患者复合治疗中的临床疗效。对 97 名结肠远端各种炎症性疾病患者的药物治疗结果进行了对比分析,这些患者被分为两组。46 名(47.4%)I 组(对照组)患者使用基本抗炎药物进行标准药物治疗;51 名(52.6%)II 组(主要组)患者在标准药物治疗方案的基础上向直肠内注入透明质酸钠药物(1 毫升中含有 0.8 毫克透明质酸)。治疗结果的比较评估考虑了疾病的临床、实验室和内窥镜表现的严重程度。与对照组患者相比,主要治疗组患者的远端结肠黏膜糜烂和溃疡愈合时间明显缩短(分别为 29.4 ± 5.7 天和 52.8 ± 6.2 天)。此外,主治组患者的临床和化验指标也得到了稳定缓解,恢复了工作能力,提高了生活质量。我们所获得的结果使我们能够推荐透明质酸钠药物作为门诊治疗各种炎症性远端结肠慢性疾病的附加外用药物。
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引用次数: 0
Possible complications associated with the use of cyanoacrylate obliteration in patients with varicose veins 静脉曲张患者使用氰基丙烯酸酯抹去静脉曲张可能出现的并发症
Pub Date : 2024-05-17 DOI: 10.21518/akh2024-002
B. Boldin, V. Bogachev, S. V. Rodionov, P. Turkin, A. A. Slesareva, P. Y. Golosnitskiy, I. M. Dizengof, G. A. Varich
The problem of finding an ideal method for the correction of vertical venous reflux in lower extremity varicose disease is highly relevant due to the rapid development of technologies and the opening of new treatment methods, including minimally invasive ones. According to many researchers, the main parameters for choosing the optimal surgical technique should be low invasiveness, compliance with the anatomical, including ultrasound, picture, the possibility of using local anesthesia, taking into account concomitant pathology and individual intolerance of various drugs by patients, effectiveness of venous vessel obliteration, and minimal risk of possible complications. The review considers a comparative characterization of endovascular treatment methods for varicose disease, as well as lists the main possible complications of each of them. In terms of obliteration effectiveness and the least pronounced complications, the leading position is occupied by the method of cyanoacrylate obliteration. There is an increasing amount of information in the literature about the use of cyanoacrylate composite in the treatment of lower extremity varicose disease. Since this method is relatively new, the number of publications describing complications of this procedure is increasing. We describe a number of specific adverse events that occur during this surgery (extravasation of cyanoacrylate composite with the formation of aseptic granulomas and, in some cases, phlebitis-like phenomena, formation of rigid subcutaneous bands limiting mobility in the knee joint, migration of cyanoacrylate into the deep venous system of the lower extremities), possible mechanisms of their occurrence, and various approaches to treatment. Special attention is paid to proximal migration of cyanoacrylate composite into the area of the saphenofemoral junction, with a description of a specific clinical case and a discussion of further management tactics for this category of patients.
由于技术的快速发展和新治疗方法(包括微创方法)的开创,寻找一种理想的方法来矫正下肢静脉曲张疾病中的垂直静脉回流问题变得非常重要。许多研究人员认为,选择最佳手术技术的主要参数应该是低创、符合解剖学(包括超声)图像、使用局部麻醉的可能性、考虑到并发病症和患者对各种药物的不耐受性、静脉血管阻塞的有效性以及可能出现并发症的最小风险。综述对静脉曲张的血管内治疗方法进行了比较,并列出了每种方法可能出现的主要并发症。就阻塞效果和最不明显的并发症而言,氰基丙烯酸酯阻塞法占据领先地位。关于使用氰基丙烯酸酯复合材料治疗下肢静脉曲张疾病的文献信息越来越多。由于这种方法相对较新,因此描述这种手术并发症的文献数量也在不断增加。我们介绍了该手术中出现的一些特殊不良事件(氰基丙烯酸酯复合材料外渗,形成无菌性肉芽肿,在某些情况下还会出现类似静脉炎的现象;形成僵硬的皮下带,限制膝关节的活动;氰基丙烯酸酯迁移到下肢深静脉系统)、可能的发生机制以及各种治疗方法。其中特别关注了氰基丙烯酸酯复合材料向隐股骨交界处的近端迁移,并描述了一个具体的临床病例,还讨论了针对这类患者的进一步治疗策略。
{"title":"Possible complications associated with the use of cyanoacrylate obliteration in patients with varicose veins","authors":"B. Boldin, V. Bogachev, S. V. Rodionov, P. Turkin, A. A. Slesareva, P. Y. Golosnitskiy, I. M. Dizengof, G. A. Varich","doi":"10.21518/akh2024-002","DOIUrl":"https://doi.org/10.21518/akh2024-002","url":null,"abstract":"The problem of finding an ideal method for the correction of vertical venous reflux in lower extremity varicose disease is highly relevant due to the rapid development of technologies and the opening of new treatment methods, including minimally invasive ones. According to many researchers, the main parameters for choosing the optimal surgical technique should be low invasiveness, compliance with the anatomical, including ultrasound, picture, the possibility of using local anesthesia, taking into account concomitant pathology and individual intolerance of various drugs by patients, effectiveness of venous vessel obliteration, and minimal risk of possible complications. The review considers a comparative characterization of endovascular treatment methods for varicose disease, as well as lists the main possible complications of each of them. In terms of obliteration effectiveness and the least pronounced complications, the leading position is occupied by the method of cyanoacrylate obliteration. There is an increasing amount of information in the literature about the use of cyanoacrylate composite in the treatment of lower extremity varicose disease. Since this method is relatively new, the number of publications describing complications of this procedure is increasing. We describe a number of specific adverse events that occur during this surgery (extravasation of cyanoacrylate composite with the formation of aseptic granulomas and, in some cases, phlebitis-like phenomena, formation of rigid subcutaneous bands limiting mobility in the knee joint, migration of cyanoacrylate into the deep venous system of the lower extremities), possible mechanisms of their occurrence, and various approaches to treatment. Special attention is paid to proximal migration of cyanoacrylate composite into the area of the saphenofemoral junction, with a description of a specific clinical case and a discussion of further management tactics for this category of patients.","PeriodicalId":398195,"journal":{"name":"Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)","volume":"121 31","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141126344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Ambulatornaya khirurgiya = Ambulatory Surgery (Russia)
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