Tissue ischemia detection using impedance spectroscopy

Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Pub Date : 1994-11-03 DOI:10.1109/IEMBS.1994.415187

S. Kun, R. Peura

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引用次数: 38

Abstract

The objective of the authors' research is to develop an innovative technique for monitoring and measurement of tissue perfusion/ischemia levels. Assessment of tissue perfusion/ischemia is of critical importance in plastic and reconstructive surgery, for postoperative monitoring of transplanted muscle flaps. In order to design an instrument that would approximate as closely as possible the requirements of the "ideal" perfusion/ischemia monitor, the authors initiated research to investigate the correlation between tissue impedance measurements at various frequencies, and the tissue pH, a proven indicator of perfusion/ischemia level of the tissue. The authors' preliminary experiments were performed in vivo on rabbit anterior tibialis muscle with an impedance spectroscopic system that measures the real component of tissue impedance at seven frequencies in the range of 1 kHz to 100 kHz. The obtained results indicate that there is a strong correlation between the tissue resistivities measured, and the independent indicator of tissue ischemia.<>

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阻抗谱法检测组织缺血

作者的研究目的是开发一种创新的技术来监测和测量组织灌注/缺血水平。评估组织灌注/缺血在整形和重建手术中至关重要，用于移植肌肉瓣的术后监测。为了设计一种尽可能接近“理想”灌注/缺血监测仪要求的仪器，作者开始研究不同频率的组织阻抗测量与组织pH值之间的相关性，组织pH值是组织灌注/缺血水平的一个被证实的指标。初步实验采用阻抗光谱系统在兔胫骨前肌上进行，该系统在1 kHz至100 kHz的7个频率范围内测量组织阻抗的真实分量。所得结果表明，测得的组织电阻率与组织缺血的独立指标>之间存在很强的相关性

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Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

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