Formulation of Toothpaste Toothpaste Gel Essential Oil of Lime Leaves (Citrus Aurantifolia) With Variations Concentration of Carbomer 940 As Gelling Agent Base

Nurista Dida Ayuningtyas, A. Sudarsono, Anastasiya Sisca Yuswanti
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引用次数: 1

Abstract

Background : Lime leaves contain flavonoids, tannins, and saponins. This content is known to have activity as an antibacterial and protective of gums and teeth. Based on these activities, lime leaves can be developed as an active ingredient in gel toothpaste preparations. In the manufacture of gel toothpaste, the component that plays an important role is the gelling agent. Purpose: In this study, a variation of the gelling agent Carbomer 940 will be used to make a gel toothpaste with lime leaf extract. Methods: The independent variable used is Carbomer 940 with a variation of 3 formulas, namely 0.6%; 1.2%; and 1.8%. The evaluations carried out on gel toothpaste were organoleptic, homogeneity, pH, adhesion, spreadability and pH. Data analysis was carried out with SPSS software to see the differences between each formula. Results: The results showed that the formula 1-3 was homogeneous with a clear, homogeneous color, and a characteristic smell of menthol with a pH range of 5.85-7.49; spreading area 20.60-29.91 cm2, adhesion 6.01-35.1 seconds. The results of statistical tests with one-way ANOVA obtained a significant difference between each formula.  
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以不同浓度卡波姆940为胶凝剂的酸橙叶牙膏凝胶精油的配方研究
背景:酸橙叶含有类黄酮、单宁和皂苷。众所周知,这种成分具有抗菌和保护牙龈和牙齿的活性。基于这些活性,酸橙叶可以开发成凝胶牙膏制剂的有效成分。在凝胶牙膏的生产中,起重要作用的成分是胶凝剂。目的:在本研究中,将使用胶凝剂卡波姆940的一种变体来制作酸橙叶提取物的凝胶牙膏。方法:自变量为Carbomer 940,方差为3个公式,即0.6%;1.2%;和1.8%。对凝胶牙膏进行感官评价、均匀性评价、pH值评价、黏附性评价、涂抹性评价和pH值评价。采用SPSS软件进行数据分析,了解各配方牙膏的差异。结果:结果表明:配方1-3均质,颜色清晰均匀,具有薄荷醇的特征气味,pH值范围为5.85 ~ 7.49;扩散面积20.60-29.91 cm2,附着力6.01-35.1秒。单因素方差分析的统计检验结果表明,各公式之间存在显著差异。
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