Behavioral and Molecular Genetics of Emotion Dysregulation

L. Rappaport, S. Hawn, C. Overstreet, A. Amstadter
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引用次数: 1

Abstract

Given the critical role that emotion dysregulation plays in many psychiatric disorders, there is a need to understand the biological underpinnings of emotion regulation deficits. This chapter opens with a brief overview of emotion regulation and constructs that fall under its broad umbrella. Next, it provides a brief primer of behavioral genetic research methods, summarizes existing literature regarding the heritability of emotional dysregulation, provides an overview of molecular genetic research methods, and reviews extant molecular genetic literature on emotion regulation. Finally, the chapter reviews the limitations of existing research and identifies promising areas of future inquiry that may clarify the underlying structure of emotion dysregulation and identify the role of common genetic loci in associations between emotion dysregulation and psychopathology.
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情绪失调的行为和分子遗传学
鉴于情绪失调在许多精神疾病中所起的关键作用,有必要了解情绪调节缺陷的生物学基础。本章以情绪调节和结构的简要概述开始,这些结构属于其广泛的保护伞。其次,简要介绍了行为遗传学研究方法,总结了现有关于情绪失调遗传性的文献,概述了分子遗传学研究方法,并对现有的关于情绪调节的分子遗传学文献进行了综述。最后,本章回顾了现有研究的局限性,并确定了未来研究的有希望的领域,这些领域可能会澄清情绪失调的潜在结构,并确定情绪失调和精神病理之间关联的常见遗传位点的作用。
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