Formulasi Hand Sanitizer Gel dengan Ekstrak Buah Terung Belanda (Solanum Betaceum Cav) Sebagai Antiseptik

Vivi Ramadhani Tanjung, D. Rahmawati, Alhara Yuwanda
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Abstract

Dutch eggplant fruit (Solanum Betaceum Cav) has chemical contents including alkaloids, flavonoids, tannins, saponins and triterpenoids which are known to have antibacterial activities (Rahmadina and Sudiono 2019). Based on the compounds that are owned Dutch eggplant fruit can be used as a hand antiseptic. This study aims to formulate Dutch eggplant fruit extract (Solanum betaceum Cav) in the form of hand sanitizer preparations. Gel Hand sanitizer extract Dutch eggplant fruit is formulated with different concentrations. The method used is the Disc Diffusion Method (Kirby Bauer Method). Gel Hand sanitizer is tested for its physical properties, including Organoleptis test, homogeneity test, PH test, stability test, irritation test and antibacterial test. Hand sanitizer gel preparations that have antibacterial activity against staphylococcus aureus bacteria are at a concentration of 15%, which is 4.51 mm.
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荷兰茄子果实(Solanum Betaceum Cav)的化学成分包括生物碱、类黄酮、单宁、皂苷和三萜,已知这些物质具有抗菌活性(Rahmadina和Sudiono 2019)。根据荷兰茄子果实所含的化合物,可以用作手部防腐剂。本研究旨在研制荷兰茄子果提取物(Solanum betaceum Cav)作为洗手液制剂。荷兰茄子果提取液按不同浓度配制而成。所使用的方法是圆盘扩散法(Kirby Bauer法)。凝胶洗手液的物理性能测试,包括感官测试、均匀性测试、PH测试、稳定性测试、刺激性测试和抗菌测试。对金黄色葡萄球菌具有抗菌活性的洗手液凝胶制剂浓度为15%,即4.51 mm。
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