Locally Advanced of Periampullary Tumour...Is Curable?

Abstract

Background: Pancreatic carcinoma is currently one of the deadliest of the solid malignancies and is the fourth cause of death from cancer in the United States, with a survival rate at 5 years of less than 5%. Most of cases diagnosed as advanced with vascular encasement or invasion and have chemotherapy for down staging to increase liability of resection with good results. Materials and Methods: 20 patients with diagnosis of locally advanced pancreatic carcinoma was examined and planned prospective to detect results of treatment and curability with prognosis in a period between start of January 2016 to end of December 2017. Conclusion: Pancreatic carcinoma may be curable with the use of MDT for treatment and neoadjuvant with surgery and vascular resection with follow up with CT, PET-CT and markers CA19.9 with good results and prognosis. Results: 20 patients included in this study, diagnosed as pancreatic head carcinoma in 10/20 (50%) and periampullary carcinoma in 10/20 (50%) of patients, all patients were diagnosed as locally advanced pancreatic cancer by radiological staging and diagnosis, 14/20 (70%) was males and 6/20 (30%) female, the age of patients at diagnosis was 39-62 years with median age 51 years.