Discrete Bilal Distribution in the Presence of Right-Censored Data and a Cure Fraction

Bruno Caparroz Lopes de Freitas, J. Achcar, Marcos Vinicius de Oliveira Peres, E. Martinez
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Abstract

The statistical literature presents many continuous probability distributions with only one parameter, which are extensively used in the analysis of lifetime data, such as the exponential, the Lindley, and the Rayleigh distributions. Alternatively, the use of discretized versions of these distributions can provide a better fit for the data in many applications. As the novelty of this study, we present inferences for the discrete Bilal distribution (DB) with one parameter introduced by Altun et al. (2020) in the presence of right-censored data and cure fraction. We assume standard maximum likelihood methods based on asymptotic normality of the maximum likelihood estimators and also a Bayesian approach based on MCMC (Markov Chain Monte Carlo) simulation methods to get inferences for the parameters of the discrete BD distribution. The use of the proposed model was illustrated with three examples considering real medical lifetime data sets. From these applications, we concluded that the proposed model based on the discrete DB distribution has good performance even with the inclusion of a cure fraction in comparison to other existing discrete models, such as the DsFx-I, Lindley, Rayleigh, and Burr-Hatke probability distributions. Moreover, the model can be easily implemented in standard existing software, such as the R package. Under a Bayesian approach, we assumed a gamma prior distribution for the parameter of the DB discrete distribution. We also provided a brief sensitivity analysis assuming the half-normal distribution in place of the gamma distribution for the parameter of the DB distribution. From the obtained results of this study, we can conclude that the proposed methodology can be very useful for researchers dealing with medical discrete lifetime data in the presence of right-censored data and cure fraction.
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右截数据和治愈分数存在下的离散双侧分布
统计文献提出了许多只有一个参数的连续概率分布,这些分布广泛应用于寿命数据的分析,如指数分布、林德利分布和瑞利分布。另外,使用这些分布的离散版本可以更好地适应许多应用程序中的数据。作为本研究的新颖之处,我们在右截尾数据和治愈分数存在的情况下,用Altun等人(2020)引入的一个参数对离散双侧分布(DB)进行了推断。我们采用基于极大似然估计量渐近正态性的标准极大似然方法和基于MCMC(马尔可夫链蒙特卡罗)模拟方法的贝叶斯方法来推断离散BD分布的参数。用三个考虑真实医疗寿命数据集的例子说明了该模型的应用。从这些应用中,我们得出结论,与其他现有的离散模型(如DsFx-I、Lindley、Rayleigh和Burr-Hatke概率分布)相比,基于离散DB分布的拟议模型即使包含固化分数,也具有良好的性能。此外,该模型可以很容易地在标准的现有软件中实现,例如R包。在贝叶斯方法下,我们假设DB离散分布的参数为gamma先验分布。我们还提供了一个简短的灵敏度分析,假设DB分布的参数以半正态分布代替gamma分布。从本研究获得的结果中,我们可以得出结论,所提出的方法对于研究人员在存在右删节数据和治愈分数的情况下处理医疗离散寿命数据非常有用。
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