Criteria for Rational Use of Antibiotics in Over Aggregated Bacterial Infection in Covid-19

Abstract

The use of antibacterials, in almost all COVID cases that require hospitalization, has been widespread throughout the planet despite being a viral infection verified by molecular biology and tomographic images characteristic of bilateral atypical pneumonia. The WHO recommended using empirical antibiotic therapy "against all the most frequent pathogens" in cases of COVID pneumonia that require hospitalization. This abuse will have dire consequences on the bacterial flora due to selection pressure, mainly of extended spectrum beta-lactamase-producing Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter baumanii and other multi-resistant bacteria. Some criteria or guidelines are proposed to decide or not the administration of antibacterials to cases of COVID with respiratory failure and need for hospitalization.