Prevalence of non-motor disorders in Parkinson`s disease

N. Y. Safonova, M. R. Sapronova, O. Gavrilyuk, T. Popova, A. Tappakhov
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Abstract

(1) Background: to reveal the prevalence of non-motor disorders in Parkinson’s disease (PD), we analyzed both Russian and international studies on the issue of PD-associated non-motor disorders in Caucasian patients; (2) Methods: We have carried out a search for full-text Englishand Russian-language articles published during the last ten years (from 2010 to 2020) in PubMed, Scopus, Web of Science, Springer, Clinical case, and E-library databases using multiple versions of keywords and their combinations. (3) Results: General prevalence of PD-associated non-motor disorders proved to be high. At the same time, we did not find significant differences between the prevalence of cognitive, affective, or behavioral disorders in PD patients. However, depression was found to be more common in PD patients in the Russian Federation; (4) Conclusions: According to the results of our review, cognitive and affective disorders in PD represent the issues of major concern. 
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帕金森病非运动障碍的患病率
(1)背景:为了揭示帕金森病(PD)非运动障碍的患病率,我们分析了俄罗斯和国际上关于白种人PD相关非运动障碍问题的研究;(2)方法:使用多个版本的关键词及其组合,对PubMed、Scopus、Web of Science、Springer、Clinical case和E-library数据库中近十年(2010 - 2020年)发表的英文和俄文全文文章进行检索。(3)结果:pd相关非运动障碍的普遍患病率较高。同时,我们没有发现PD患者中认知、情感或行为障碍的患病率有显著差异。然而,抑郁症在俄罗斯联邦PD患者中更为常见;(4)结论:根据我们的综述结果,PD的认知和情感障碍代表了主要关注的问题。
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