Atypical Structure of Broca's Area in a Patient with Primary Progressive Atrophy Syndrome at the Onset of Alzheimer's Disease

Y. V. Kotsiubinskaya, V. V. Vasilev, A. V. Kazakov, I. K. Stulov, V. A. Mikhailov
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Abstract

This article presents a clinical case of Alzheimer’s disease with a debut as primary progressive aphasia syndrome. Insufficient use of routine magnetic resonance imaging in this case in the diagnosis of neurodegenerative diseases and the advantage of such additional neuroimaging methods as positron emission tomography, functional magnetic resonance imaging with a scale assessment of atrophic changes. Additional neuroimaging techniques have been shown to significantly improve the early detection of pathological changes in brain structures and to reveal the location of functional areas involved in the neurodegenerative process.
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阿尔茨海默病发病时原发性进行性萎缩综合征患者布洛卡区的非典型结构
本文介绍了一个以原发性进行性失语综合征为首发症状的阿尔茨海默病临床病例。在该病例中,常规磁共振成像在神经退行性疾病诊断中的应用不足,而正电子发射断层扫描、功能磁共振成像与萎缩性病变的规模评估等其他神经影像学方法则具有优势。事实证明,附加的神经成像技术能显著提高早期发现大脑结构病理变化的能力,并揭示神经退行性病变过程中的功能区位置。
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