Dispersion of Solute in Casson Fluid through a Stenosed Artery with the Effect of Body Acceleration

Nuur Atikah Elias, Nurul Aini Jaafar, Intan Diyana Munir, Sharidan Shafie
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Abstract

Body acceleration and slip velocity effects towards the dispersion of solute in Casson blood flow through a stenosed artery is investigated mathematically. Momentum and constitutive equations are solved analytically to obtain the blood velocity. Convective-diffusion equation is solved using Generalized Dispersion Model to obtain dispersion function and mean concentration of solute. A study has been conducted on how body acceleration and slip velocity disturb the dispersion of a solute in blood flow. With the increase of slip velocity and body acceleration, blood velocity increases. The impact of body acceleration on blood flow is to increase flow rate while lowering resistance to flow. Casson fluid is a suitable fluid model to examine the blood velocity and drug transport to the targeted problematic region through a narrow artery for the treatment of arterial diseases. The findings of the present study can be beneficial for pharmaceutical research to design better drug by referring mathematical analysis data that produced in this study.
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卡森液中溶质通过狭窄动脉的分散与身体加速度的影响
用数学方法研究了体加速度和滑移速度对狭窄动脉血流中溶质弥散的影响。对动量方程和本构方程进行解析求解,得到血流速度。采用广义色散模型求解对流扩散方程,得到色散函数和溶质平均浓度。一项关于身体加速度和滑移速度如何干扰溶质在血流中的分散的研究已经进行了。随着滑移速度和体加速度的增大,血流速度增大。身体加速对血流的影响是在增加血流速率的同时降低血流阻力。卡森液是检测血液流速和药物通过狭窄动脉输送到目标问题区域的一种合适的流体模型,用于动脉疾病的治疗。本研究结果可为药学研究提供参考,以设计出更好的药物。
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