Imaging of human oral cancer using multiphoton microscopy

Abstract

Due to the growing importance of optical imaging in tissue diagnosis, we use multiphoton microscopy, to characterize normal and cancerous oral tissues. We acquired both microscopic and spectroscopic data for the characterization of normal and cancerous oral tissues. Our results show that both multiphoton fluorescence and harmonic generation images may be used to distinguish both tissue types. An image of different oral tissues will be of value for clinicians in the diagnosis and treatment of oral diseases.