The Beneficial Effects of Photobiomodulation to Reduce Intraocular Pressure in Primary Open-Angle Glaucoma

A. C. Boudghene, T. Ahmed, K. Belbachir, H. Ghalia
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Abstract

Purpose: The aim of this trail was to study the efficacy of photobiomodulation (PBM) treatment to reduce the intraocular pressure in subjects with primary open angle glaucoma disease. Methods: Twenty eyes suffering from open angle glaucoma with high IOP level were selected, examined and treated with Thera-RED light diode system. The subjects were divided into two groups (n=10); treated and placebo group respectively; this system provide two lights (red at 660n.m continue and Near IR light micro-pulsed at 850 n.m), the patients received two series of treatment (ten per month within three months between every series of sessions) over five months and follow up taking ocular pressure measurements after every diode delivery session. Results: A significant decrease in IOP has been observed from the first month of the treatment compared to the placebo group (from 22.6mmHg before treatment to 15 mmHg after the tenth session) this amelioration has been also remarked during the second session of treatment (fifth month) to attempt 14.2 mmHg.  Conclusion: Thera-RED light diode system  treatment shows a significant  decrease of  IOP and remained to be stable under 14.2 mmHg in all the follow up, which  confirm that photobiomodulation  help in reducing   the intraocular pressure  in glaucomatous patients .
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光生物调节对原发性开角型青光眼降低眼压的有益作用
目的:研究光生物调节(PBM)治疗原发性开角型青光眼患者降低眼压的疗效。方法:选择高IOP的开角型青光眼20只眼,采用Thera-RED光二极管系统进行检查和治疗。将受试者分为两组(n=10);治疗组和安慰剂组;该系统提供两盏灯(660度红光)。在5个月的时间里,患者接受了两个系列的治疗(每个系列之间的三个月内每月10次),并在每次二极管交付后进行了眼压测量。结果:与安慰剂组相比,治疗的第一个月IOP显著下降(从治疗前的22.6mmHg降至第十次治疗后的15 mmHg),这种改善在第二次治疗(第五个月)期间也被观察到,达到14.2 mmHg。结论:经Thera-RED光二极管系统治疗后,眼压明显降低,并稳定在14.2 mmHg以下,证实光生物调节有助于降低青光眼患者的眼压。
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