T. Prow, Xianfeng Chen, M. Crichton, Y. Tiwari, F. Gradassi, K. Raphelli, D. Mahony, G. Fernando, M. Roberts, M. Kendall
{"title":"Targeted epidermal delivery of vaccines from coated micro-nanoprojection patches","authors":"T. Prow, Xianfeng Chen, M. Crichton, Y. Tiwari, F. Gradassi, K. Raphelli, D. Mahony, G. Fernando, M. Roberts, M. Kendall","doi":"10.1109/ICONN.2008.4639262","DOIUrl":null,"url":null,"abstract":"Transcutaneous vaccine delivery has the potential to greatly improve immunization effectiveness and safety. This work characterizes our novel micro-nanoneedles and their payload release profile in vitro and in vivo. We found that these dry-coated micro-nanoneedles quickly deliver the payload to the epidermis.","PeriodicalId":192889,"journal":{"name":"2008 International Conference on Nanoscience and Nanotechnology","volume":"82 1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2008-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2008 International Conference on Nanoscience and Nanotechnology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICONN.2008.4639262","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
Transcutaneous vaccine delivery has the potential to greatly improve immunization effectiveness and safety. This work characterizes our novel micro-nanoneedles and their payload release profile in vitro and in vivo. We found that these dry-coated micro-nanoneedles quickly deliver the payload to the epidermis.