E. Okada, H. Minamitani, Y. Fukuoka, C. Ohshio, M. Suematsu, M. Suzuki, M. Tsuchiya
{"title":"Laser Doppler microscope for high accuracy velocity measurement of microcirculation","authors":"E. Okada, H. Minamitani, Y. Fukuoka, C. Ohshio, M. Suematsu, M. Suzuki, M. Tsuchiya","doi":"10.1109/IEMBS.1988.95120","DOIUrl":null,"url":null,"abstract":"The velocity of red blood cells in the microcirculation of rat mesenteries was measured by using a laser Doppler microscope (LDM). The LDM system must be improved to provide accurate measurement, because there are some inherent disturbances on measuring the flow velocity in a microscopic area. The authors investigate the spurious Doppler signals, which are the most serious problem in LDM measurement, and develop an optical arrangement for eliminating the effect of spurious components. In vitro and in vivo microscopic flow measurements showed that the impaired system provides high-accuracy velocity measurement for a microscopic area.<<ETX>>","PeriodicalId":227170,"journal":{"name":"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IEMBS.1988.95120","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
The velocity of red blood cells in the microcirculation of rat mesenteries was measured by using a laser Doppler microscope (LDM). The LDM system must be improved to provide accurate measurement, because there are some inherent disturbances on measuring the flow velocity in a microscopic area. The authors investigate the spurious Doppler signals, which are the most serious problem in LDM measurement, and develop an optical arrangement for eliminating the effect of spurious components. In vitro and in vivo microscopic flow measurements showed that the impaired system provides high-accuracy velocity measurement for a microscopic area.<>
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